Results 121 to 130 of about 271,709 (284)

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

The journey to improving stroke risk stratification for patients with carotid artery stenosis: from medical management to revascularization

Hellenic Journal of Cardiology
Ischemic strokes remain a leading cause of mortality and morbidity worldwide. Carotid artery stenosis is a major risk factor for ischemic strokes. Although traditional carotid revascularization procedures are based on carotid stenosis, it has been ...
Ioanna Gianopoulos, Stella S. Daskalopoulou   +1 more
doaj   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Using natural language processing to extract carotid stenosis severity from clinical notes to create a nationwide veteran cohort

JVS-Vascular Insights
Objective: The prevalence of moderate to severe asymptomatic carotid stenosis (ie, atherosclerotic narrowing of the extracranial carotid arteries) is generally approximately 6% and 2%, respectively.
Kyung Min Lee, PhD, MPH, Patrick R. Alba, MS, Gina M. Biagetti, MD, Anthony Gao, BS, Ming Yin, MS, Peter N. Danilov, BA, Tia DiNatale, MPH, Cristina Perez, MS, Katherine Hartmann, MD, PhD, Gabrielle E. Shakt, BS, Renae L. Judy, MS, Tiffany R. Bellomo, MD, Kathryn M. Pridgen, MA, Philip S. Tsao, PhD, Naveen Balasundaram, MD, Michael G. Levin, MD, Scott M. Damrauer, MD, Julie A. Lynch, PhD, RN, MBA   +17 more
doaj   +1 more source

Current strategies to enhance the target efficiency of advanced multifunctional ultrasound contrast agents in ischemic diseases

Interdisciplinary Medicine, EarlyView.
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou, Jing Lin, Yu Chen, Jiaqi Zhao   +3 more
wiley   +1 more source

Endovascular Revascularization of Chronic Cervical Carotid Occlusion

, 2023
STROKE: Vascular and Interventional Neurology, EarlyView.
Sami Al Kasab, Brian Jankowitz
wiley   +1 more source

Neuroprotective effects of quercetin in animal models of neurodegenerative diseases: A systematic review and meta‐analysis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho, Hendra Mahakam Putra, Cheol Woon Jung, Gyu Hwan Hyun, Hwan‐Hee Jang, In Guk Hwang, Sung Won Kwon   +6 more
wiley   +1 more source

Management of carotid stenosis. History and today [PDF]

, 2013
Internal carotid stenosis constitutes a significant clinical challenge, since it is the cause of 20–25% of ischemic brain strokes. The management of the internal carotid stenosis for many years has been raising controversies amongst neurologists ...
Drelich-Zbroja, Anna, Tomasz Jargiełło, Małgorzata Szczerbo-Trojanowska, Jargiełło, Tomasz, Anna Drelich-Zbroja, Szczerbo-Trojanowska, Małgorzata   +5 more
core  

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Evaluation of Burden of Carotid Artery Disease In Ischemic Stroke Patients With And Without Hypertension

Pakistan Armed Forces Medical Journal
Objective: To evaluate the burden of carotid artery stenosis in ischemic stroke patients and its association with socio-demographic aspects of Hypertension. Place and Duration of Study: Tertiary Care Hospital, Rawalpindi Pakistan, from Jan to Jun 2020.
Hamad Khan, Khurram Haq Nawaz, Asif Hashmat, Hamid Mukhtar, Fawad Ahmad, Muhammad Anjum   +5 more
doaj   +1 more source