Results 51 to 60 of about 543,713 (327)

Association of Transcarotid Artery Revascularization vs Transfemoral Carotid Artery Stenting With Stroke or Death Among Patients With Carotid Artery Stenosis.

Journal of the American Medical Association (JAMA), 2019
Importance Several trials have observed higher rates of perioperative stroke following transfemoral carotid artery stenting compared with carotid endarterectomy. Transcarotid artery revascularization with flow reversal was recently introduced for carotid
M. Schermerhorn, Patric Liang, J. Eldrup-Jorgensen, J. Cronenwett, B. Nolan, V. Kashyap, Grace J. Wang, R. Motaganahalli, M. Malas   +8 more
semanticscholar   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

Advanced Science, EarlyView.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang, Yujie Shan, Shihong Xu, Jing Wang, Meng Luo, Jiaojiao Zhou, Qishan Chen   +6 more
wiley   +1 more source

Carotid atherosclerotic disease: A systematic review of pathogenesis and management

Brain Circulation, 2022
Carotid stenosis is an important contributor to ischemic stroke risk with resultant significant impact on neurological disability and death in adults and with worldwide implications.
Shyamal C Bir, Roger E Kelley
doaj   +1 more source

Carotid Stenosis: An Unknown Disease… [PDF]

European Journal of Vascular and Endovascular Surgery, 2012
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openaire   +4 more sources

Identification of Schwann Cells in Human Intracranial Arteries: Potential Regulatory Role in Atherosclerotic Plaque Progression

Advanced Science, EarlyView.
Schwann cells may facilitate intracranial plaque progression via neurovascular remodelingcting with vascular smooth muscle cells in atherosclerotic plaques, with the SPP1 ‐ ITGB1 signaling axis mediating this interaction as a novel mechanism. Abstract Intracranial atherosclerosis (ICAS), a common cause of ischemic stroke, remains a therapeutic ...
Zijue Wang, Yangzhige He, Weizhuang Yuan, Yijun Xia, Manqiu Ding, Zhen Chen, Naili Wang, Chao Ma, Xiaoyue Wang, Yan Xu, Weihai Xu   +10 more
wiley   +1 more source

Carotid artery stenosis

BMJ, 2010
Carotid endarterectomy is currently the most effective intervention to prevent stroke in patients with recent symptoms of carotid stenosis.1 2 It also prevents future stroke in younger patients (under 75 years) who have not yet had symptoms, as long as the risk of stroke and death from surgery is not more than 3% Patients naturally prefer carotid ...
Halliday, A, Norris, J
openaire   +3 more sources

Angioplasty in asymptomatic carotid artery stenosis vs. endarterectomy compared to best medical treatment: One-year interim results of SPACE-2

International Journal of Stroke, 2019
Background Treatment of individuals with asymptomatic carotid artery stenosis is still handled controversially. Recommendations for treatment of asymptomatic carotid stenosis with carotid endarterectomy (CEA) are based on trials having recruited patients
T. Reiff, H. Eckstein, Ulrich Mansmann, O. Jansen, G. Fraedrich, H. Mudra, D. Böckler, M. Böhm, H. Brückmann, E. S. Debus, J. Fiehler, W. Lang, K. Mathias, E. Ringelstein, J. Schmidli, R. Stingele, R. Zahn, T. Zeller, A. Hetzel, U. Bodechtel, Andreas Binder, J. Glahn, W. Hacke, P. Ringleb   +23 more
semanticscholar   +1 more source

Shear Stress Targeted Delivery of Nitroglycerin to Brain Collaterals Improves Ischaemic Stroke Outcome

Advanced Science, EarlyView.
Shear‐activated nanoparticles carrying nitroglycerin selectively target high‐shear stress collateral vessels during ischaemic stroke, enhancing blood flow to at‐risk brain without systemic side effects. This novel approach significantly improves outcomes in animal models, outperforming conventional nitroglycerin delivery.
Magdalena Litman, Sara Azarpeykan, Rebecca J Hood, Kristy Martin, Debbie Pepperall, Daniel Omileke, Fern Williams, Oktay Uzun, Deen Bhatta, Yuen K Yong, Alex Chan, Nicholas Hough, Sarah Johnson, Pablo Garcia Bermejo, Ferdinand Miteff, Carlos Garcia Esperon, Yvonne Couch, Alastair M Buchan, Neil J Spratt, Netanel Korin, Donald E Ingber, Daniel J Beard   +21 more
wiley   +1 more source

Blood Flow Lateralization and Collateral Compensatory Mechanisms in Patients With Carotid Artery Stenosis

Stroke, 2019
Background and Purpose— Four-dimensional phase-contrast magnetic resonance imaging enables quantification of blood flow rate (BFR; mL/min) in multiple cerebral arteries simultaneously, making it a promising technique for hemodynamic investigation in ...
L. Zarrinkoob, A. Wåhlin, K. Ambarki, R. Birgander, A. Eklund, J. Malm   +5 more
semanticscholar   +1 more source

A Single‐Component Adhesive Sponge Based on Blood‐Triggered and Autopenetrative Adhesion for Robust Vascular Closure

Advanced Science, EarlyView.
This study presents MonoSeal, a single‐component adhesive sponge powered by the novel Autopenetrative Adhesion (APA) mechanism. Unlike traditional adhesives, which require external stimuli, APA enables strong tissue adhesion under dynamic, high‐pressure bleeding conditions. MonoSeal's ability to autonomously seal large‐size arterial defects underscores
Rong Wang, Weishi Zheng, Yuxuan Huang, Rui Zhang, Yi Zhang, Jingying Yan, Yuqing Gu, Jingyun Xi, Tun Yuan, Hua Su, Xianzhu Zhang, Xiaozhao Wang, Shaohui Xiong, Zhenfeng Cheng, Hongwei Ouyang, Yi Hong   +15 more
wiley   +1 more source