Results 51 to 60 of about 594,565 (335)

Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque [PDF]

, 2018
Experimental studies showed that gut-derived lipopolysaccharide (LPS) is pro-atherogenic, however, its relationship with human atherosclerosis is still to be defined.
Cammisotto, Vittoria, Carnevale, Roberto, Frati, Giacomo, Irace, Luigi, Martinelli, Ombretta, Nocella, Cristina, Pacini, Luca, Pastori, Daniele, Petrozza, Vincenzo, Sciarretta, Sebastiano, Sorrentino, Veronica, Violi, Francesco   +11 more
core   +2 more sources

Angioplasty in asymptomatic carotid artery stenosis vs. endarterectomy compared to best medical treatment: One-year interim results of SPACE-2

International Journal of Stroke, 2019
Background Treatment of individuals with asymptomatic carotid artery stenosis is still handled controversially. Recommendations for treatment of asymptomatic carotid stenosis with carotid endarterectomy (CEA) are based on trials having recruited patients
T. Reiff, H. Eckstein, Ulrich Mansmann, O. Jansen, G. Fraedrich, H. Mudra, D. Böckler, M. Böhm, H. Brückmann, E. S. Debus, J. Fiehler, W. Lang, K. Mathias, E. Ringelstein, J. Schmidli, R. Stingele, R. Zahn, T. Zeller, A. Hetzel, U. Bodechtel, Andreas Binder, J. Glahn, W. Hacke, P. Ringleb   +23 more
semanticscholar   +1 more source

Autonomous Implants

Advanced Materials, EarlyView.
An ideal implant should mimic native tissues such that it can integrate, sense, heal, and continue to function, i.e., be autonomous. Although early, there are good steps taken in this way, e.g., the development of stimuli‐responsive, self‐powering, self‐actuating, self‐healing, self‐regenerating, and self‐aware implants.
Jagan Mohan Dodda, Marcel F. Kunrath, Ling Zhou Zhao, Mahdi Bodaghi, Armin Yousefi, Nureddin Ashammakhi   +5 more
wiley   +1 more source

Blood Flow Lateralization and Collateral Compensatory Mechanisms in Patients With Carotid Artery Stenosis

Stroke, 2019
Background and Purpose— Four-dimensional phase-contrast magnetic resonance imaging enables quantification of blood flow rate (BFR; mL/min) in multiple cerebral arteries simultaneously, making it a promising technique for hemodynamic investigation in ...
L. Zarrinkoob, A. Wåhlin, K. Ambarki, R. Birgander, A. Eklund, J. Malm   +5 more
semanticscholar   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

How to Undertake a Clinically Relevant Systematic Review in a Rapidly Evolving Field: Magnetic Resonance Angiography [PDF]

, 2002
Objectives: The aim was to determine which generations of the evolving technology of magnetic resonance angiography (MRA) are currently of clinical relevance in two clinical applications. Our purpose was to plan a systematic review that would be valuable
Airey, C.M., Bamford, J.M., Berry, E., Cullingworth, J., Davies, L.M., Gough, M.J., Kelly, S., Meaney, J.F.M., Smith, M.A., Westwood, M.E.   +9 more
core  

Natriuretic peptide receptor-C is up-regulated in the intima of advanced carotid artery atherosclerosis [PDF]

, 2016
OBJECTIVE: Natriuretic peptide receptor-C (NPR-C/NPR-3) is a cell surface protein involved in vascular remodelling that is up-regulated in atherosclerosis. NPR-C expression has not been well characterized in human carotid artery occlusive lesions.
Abendschein, Dana R, Detering, Lisa, Harring, Scott D, Liu, Yongjian, Lu, Dongsi, Vemuri, Chandu, Woodard, Pamela K, Zayed, Mohamed A   +7 more
core   +3 more sources

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Shear Stress Targeted Delivery of Nitroglycerin to Brain Collaterals Improves Ischaemic Stroke Outcome

Advanced Science, EarlyView.
Shear‐activated nanoparticles carrying nitroglycerin selectively target high‐shear stress collateral vessels during ischaemic stroke, enhancing blood flow to at‐risk brain without systemic side effects. This novel approach significantly improves outcomes in animal models, outperforming conventional nitroglycerin delivery.
Magdalena Litman, Sara Azarpeykan, Rebecca J Hood, Kristy Martin, Debbie Pepperall, Daniel Omileke, Fern Williams, Oktay Uzun, Deen Bhatta, Yuen K Yong, Alex Chan, Nicholas Hough, Sarah Johnson, Pablo Garcia Bermejo, Ferdinand Miteff, Carlos Garcia Esperon, Yvonne Couch, Alastair M Buchan, Neil J Spratt, Netanel Korin, Donald E Ingber, Daniel J Beard   +21 more
wiley   +1 more source