Results 61 to 70 of about 271,709 (284)

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Carotid Stenting Versus Endarterectomy in Symptomatic Carotid Stenosis [PDF]

Al-Azhar International Medical Journal
Background: Carotid artery stenosis is a leading cause of TIA, acute stroke, recurrent stroke and chronic cerebrovascular insufficiency, so this needs effective management.
Mohamed Mansour, Mohammed Hamed, Osama Ghazala   +2 more
doaj   +1 more source

Correlation between Carotid Artery Fat Density and Atherosclerosis

CT Lilun yu yingyong yanjiu
Objective: In this study, we aim to investigate the correlation between carotid artery fat density and atherosclerotic stenosis, providing a clinical reference for the early identification of carotid atherosclerotic stenosis.
Yuemeng LI, Weizhi CHEN
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Risk of Stroke before Revascularisation in Patients with Symptomatic Carotid Stenosis: A Pooled Analysis of Randomised Controlled Trials: A Pooled Analysis of Randomised Controlled Trials

, 2021
OBJECTIVE: Current guidelines recommending rapid revascularisation of symptomatic carotid stenosis are largely based on data from clinical trials performed at a time when best medical therapy was potentially less effective than today.
Carotid Stenosis Trialists’ Collaboration
core  

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Microvascular damage is associated with carotid wall structural changes in Systemic Sclerosis: a capillaroscopy and ultrasound‐based observational study

Arthritis Care &Research, Accepted Article.
Introduction Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source

Does Carotid Atherosclerosis Cause Tinnitus?

Haseki Tıp Bülteni, 2021
Aim:Atherosclerosis is a disease affecting the intimas of arteries. We aimed to investigate the presence of carotid atherosclerosis in patients with tinnitus as an etiologic factor of tinnitus.Methods:A total of 73 patients were included.
Güven Yıldırım, Özlem Keskin, Kürşat Murat Özcan, Tolgar Lütfi Kumral   +3 more
doaj   +1 more source

Inflammation and endothelial function relevant genetic polymorphisms in carotid stenosis in southwestern China

Frontiers in Neurology, 2023
AimTo evaluate the relationship between carotid stenosis with variants in genes referred to inflammation and endothelial function.MethodsThere was a multi-center, cross sectional survey in southwestern China. The eight communities were selected at random
Lin Liu, Xingyang Yi, Hua Luo, Ming Yu
doaj   +1 more source

The safety and performance of the new Nitinol stent in the treatment of carotid artery stenosis : one and six month follow-up [PDF]

, 2009
Background The purpose of the trial was to evaluate the safety and performance of the new Protégé stent in the treatment of common and/or internal carotid artery stenoses. Methods The Protégé® GPS stent is a self-expanding Nitinol stent system.
Franke, Jennifer
core