Results 81 to 90 of about 271,709 (284)

A Rare Form of Microcephalic Primordial Dwarfism due to NSMCE2 Deficiency (Seckel Syndrome Type 10): A Report of Macular Involvement

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto, Céline Huber, Clément Paya, Isabelle Audo, Nathalie Boddaert, Valérie Cormier‐Daire   +5 more
wiley   +1 more source

Correlation between asymptomatic intracranial arterial stenosis and carotid atherosclerosis in patients with Type 2 diabetes mellitus

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To evaluate the correlation between asymptomatic intracranial arterial stenosis and extracranial carotid atherosclerosis in patients with Type 2 diabetes mellitus (DM).
Yang SONG, Shan GAO, Ying⁃huan HU, Qing DAI, Wei⁃gang ZHAO, Li⁃ying CUI   +5 more
doaj  

Management of patients with carotid stenosis [PDF]

Pathophysiology of Haemostasis and Thrombosis, 2002
Carotid atherosclerosis is one of the main risk factors for ischemic stroke. The annual risk of ipsilateral stroke for asymptomatic, albeit severe stenoses is as low as 1 to 2%, but increases to 13% in patients with recent ischemic symptoms. However the risk decreases after the first 2-3 years from the symptomatic episode, dropping to 3%.
De Fabritiis, A., Conti, E., Coccheri, S.   +2 more
openaire   +3 more sources

Predictors and clinical significance of progression or regression of asymptomatic carotid stenosis.

, 2014
To determine baseline clinical and ultrasonographic plaque factors predictive of progression or regression of asymptomatic carotid stenosis and the predictive value of changes in stenosis severity on risk of first ipsilateral cerebral or retinal ischemic
Nicolaides AN, Naylor AR, Charalambous I, AROSIO, Enrico, Thomas D, Abbott AL, Kakkos SK, Asymptomatic Carotid Stenosis, Risk of Stroke Study Group, Giannopoulos A, Geroulakos G   +10 more
core   +1 more source

Ocular ischemic syndrome with bilateral carotid artery stenosis in a patient with chronic tophaceous gout

, 2023
Ocular ischaemic syndrome is a rare, blinding condition which usually presents rather late. This occurs mainly due to stenosis or occlusion of the carotid artery which supplies the ocular structures.
Md Saleh, Rafidah, Mohamed Shafit, Muhammad Adri, Mohammad Razali, Amirah, Mohmood, Adzleen, Mohd Isa, Mujammad   +4 more
core   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Carotid stenosis: what is the high-risk population?

Clinics
OBJECTIVE: Prevention is the best treatment for cerebrovascular disease, which is why early diagnosis and the immediate treatment of carotid stenosis contribute significantly to reducing the incidence of stroke.
Jong Hun Park, Alvaro Razuk, Paulo Fernandes Saad, Gustavo José Politzer Telles, Walter Khegan Karakhanian, Alexandre Fioranelli, Alessandra Caivano Rodrigues, Giuliano Giova Volpiani, Pollyanna Campos, Roberto Massayoshi Yamada, Valter Castelli Jr., Roberto Augusto Caffaro   +11 more
doaj   +1 more source

Risk stratification of patients with asymptomatic carotid artery stenosis: evaluation of carotid stenosis severity, progression, and morphology by duplex ultrasound

, 2007
The evaluation of patients harboring significant carotid atherosclerotic disease entails a careful evaluation of the likely mechanism(s) leading to the increased risk of future stroke.

core   +2 more sources

Age‐Associated B Cells Contribute to Inflammation Via Antibody‐Independent Mechanisms in Takayasu Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Although Takayasu arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B cell activation and its contributions to TAK pathogenesis. Methods Histologic analysis of paravascular lymph nodes and affected arteries was conducted
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao, Jing Li, Zhen Chen, Yuexin Chen, Mengtao Li, Xinping Tian   +10 more
wiley   +1 more source