Results 81 to 90 of about 652,739 (324)

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Interobserver agreement for 10% categories of angiographic carotid stenosis [PDF]

, 1997
BACKGROUND AND PURPOSE: Although the reliability of the assessment of severe 70% to 99% carotid stenosis by carotid angiography has been proven excellent, this may not necessarily be the case for a more detailed classification of carotid stenoses by 10 ...
Bakker, S.L.M. (Stef), Dippel, D.W.J. (Diederik), Kooten, F. (Fop) van, Koudstaal, P.J. (Peter)   +3 more
core   +2 more sources

Optimization of Magnetic Milli‐Spinner for Robotic Endovascular Intervention

Advanced Robotics Research, EarlyView.
This work presents the design optimization of a multifunctional magnetic milli‐spinner for high‐speed propulsion and efficient clot debulking. The optimized design achieves an ultrafast swimming velocity of 55 cm/s (≈175 body lengths/s) in saline water, enabling stable upstream swimming against strong physiological flows and establishing magnetic milli‐
Lu Lu, Luca Higgins, Jack Bernardo, Ruike Renee Zhao   +3 more
wiley   +1 more source

Does Carotid Atherosclerosis Cause Tinnitus?

Haseki Tıp Bülteni, 2021
Aim:Atherosclerosis is a disease affecting the intimas of arteries. We aimed to investigate the presence of carotid atherosclerosis in patients with tinnitus as an etiologic factor of tinnitus.Methods:A total of 73 patients were included.
Güven Yıldırım, Özlem Keskin, Kürşat Murat Özcan, Tolgar Lütfi Kumral   +3 more
doaj   +1 more source

Comparison of multidetector-row computed tomography and duplex Doppler ultrasonography in detecting atherosclerotic carotid plaques complicated with intraplaque hemorrhage [Usporedba višeslojne kompjuterizirane tomografije i duplex Doppler ultrazvuka u otkrivanju aterosklerotskih karotidnih plakova kompliciranih krvarenjem u plak ] [PDF]

, 2013
This study compared sensitivity and specificity of multidetector-row computed tomography and duplex Doppler ultrasonography in detecting atherosclerotic carotid plaques complicated with intraplaque hemorrhage.
Ajduk, Marko, Brkljačić, Boris, Bulimbašić, Stela, Ivanac, Gordana, Patrlj, Leonardo, Pavić, Ladislav, Pavić, Predrag, Čikara, Igor, Šarlija, Mirko   +8 more
core  

Practice patterns for acute ischemic stroke workup: A longitudinal population‐based study [PDF]

, 2017
Background We examined practice patterns of inpatient testing to identify stroke etiologies and treatable risk factors for acute ischemic stroke recurrence. Methods and Results
Adeoye, Opeolu, Alwell, Kathleen, Broderick, Joseph P, Ferioli, Simona, Flaherty, Matthew L, Khatri, Pooja, Khoury, Jane C, Kissela, Brett M, Kleindorfer, Dawn O, Loftspring, Matthew C, Moomaw, Charles J, Woo, Daniel   +11 more
core   +2 more sources

Angioplasty in asymptomatic carotid artery stenosis vs. endarterectomy compared to best medical treatment: One-year interim results of SPACE-2

International Journal of Stroke, 2019
Background Treatment of individuals with asymptomatic carotid artery stenosis is still handled controversially. Recommendations for treatment of asymptomatic carotid stenosis with carotid endarterectomy (CEA) are based on trials having recruited patients
T. Reiff, H. Eckstein, Ulrich Mansmann, O. Jansen, G. Fraedrich, H. Mudra, D. Böckler, M. Böhm, H. Brückmann, E. S. Debus, J. Fiehler, W. Lang, K. Mathias, E. Ringelstein, J. Schmidli, R. Stingele, R. Zahn, T. Zeller, A. Hetzel, U. Bodechtel, A. Binder, J. Glahn, W. Hacke, P. Ringleb   +23 more
semanticscholar   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Inflammation and endothelial function relevant genetic polymorphisms in carotid stenosis in southwestern China

Frontiers in Neurology, 2023
AimTo evaluate the relationship between carotid stenosis with variants in genes referred to inflammation and endothelial function.MethodsThere was a multi-center, cross sectional survey in southwestern China. The eight communities were selected at random
Lin Liu, Xingyang Yi, Hua Luo, Ming Yu
doaj   +1 more source

Ezetimibe therapy: mechanism of action and clinical update. [PDF]

, 2012
The lowering of low-density lipoprotein cholesterol (LDL-C) is the primary target of therapy in the primary and secondary prevention of cardiovascular events.
Dayspring, Thomas D, Phan, Binh An P, Toth, Peter P   +2 more
core   +1 more source