Genetic and molecular architecture of familial hypercholesterolemia
Abstract Atherosclerotic cardiovascular disease is the leading cause of death globally. Despite its important risk of premature atherosclerosis and cardiovascular disease, familial hypercholesterolemia (FH) is still largely underdiagnosed worldwide. It is one of the most frequently inherited diseases due to mutations, for autosomal dominant forms, in ...
Marianne Abifadel, Catherine Boileau
wiley +1 more source
Longitudinal wall shear stress evaluation using centerline projection approach in the numerical simulations of the patient-based carotid artery [PDF]
In this numerical study areas of the carotid bifurcation and of a distal stenosis in the internal carotid artery are closely observed to evaluate the patient's current risks of ischemic stroke. An indicator for the vessel wall defects is the stress the blood is exerting on the surrounding vessel tissue, expressed standardly by the amplitude of the wall
arxiv
Asymptomatic severe carotid stenosis [PDF]
The management of asymptomatic carotid stenosis remains controversial. From December 1983 to December 1987, 188 symptom-free patients were found to have severe (greater than 75%) stenosis by duplex imaging (performed as screening examination). Patients with non-hemispheric symptoms or contralateral symptomatic lesions (within 7 years) were excluded ...
Joseph J. Hurley+4 more
openaire +3 more sources
Redoy Ranjan,1,2 Dipannita Adhikary,2 Debasish Das,3 Asit Baran Adhikary1 1Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh; 2Department of Medicine & Veterinary Medicine, The University of Edinburgh ...
Ranjan R, Adhikary D, Das D, Adhikary AB
doaj
S-Nitrosoglutathione reduces asymptomatic embolization after carotid angioplasty [PDF]
Background: The major complication of carotid angioplasty is embolic stroke, which may occur after balloon inflation and deflation or in the early postintervention period.
Clifton, A.+4 more
core +1 more source
ASCORE: an up-to-date cardiovascular risk score for hypertensive patients reflecting contemporary clinical practice developed using the (ASCOT-BPLA) trial data. [PDF]
A number of risk scores already exist to predict cardiovascular (CV) events. However, scores developed with data collected some time ago might not accurately predict the CV risk of contemporary hypertensive patients that benefit from more modern ...
A K Gupta+27 more
core +1 more source
Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra+3 more
wiley +1 more source
Multi-task Deep Learning for Cerebrovascular Disease Classification and MRI-to-PET Translation [PDF]
Accurate quantification of cerebral blood flow (CBF) is essential for the diagnosis and assessment of cerebrovascular diseases such as Moyamoya, carotid stenosis, aneurysms, and stroke. Positron emission tomography (PET) is currently regarded as the gold standard for the measurement of CBF in the human brain.
arxiv
Classification of Pressure Gradient of Human Common Carotid Artery and Ascending Aorta on the Basis of Age and Gender [PDF]
The current work is done to see which artery has more chance of having cardiovascular diseases by measuring value of pressure gradient in the common carotid artery (CCA) and ascending aorta according to age and gender. Pressure gradient is determined in the CCA and ascending aorta of presumed healthy volunteers, having age between 10 and 60 years.
arxiv +1 more source
Assessment of carotid atherosclerotic disease using three-dimensional cardiovascular magnetic resonance vessel wall imaging: comparison with digital subtraction angiography. [PDF]
BACKGROUND:A three-dimensional (3D) cardiovascular magnetic resonance (CMR) vessel wall imaging (VWI) technique based on 3D T1 weighted (T1w) Sampling Perfection with Application-optimized Contrast using different flip angle Evolutions (SPACE) has ...
Fan, Zhaoyang+6 more
core +1 more source