Results 201 to 210 of about 6,262 (303)

How physiology solves the gene‐centric impasse

open access: yesExperimental Physiology, EarlyView.
Abstract The criteria for distinguishing between association and causation in studies of genes and function are clarified. Genomic association scores alone cannot satisfy those criteria, which is why treatment of common diseases has not benefitted from the cures expected when the Human Genome Project was launched.
Denis Noble, Reine Bourret
wiley   +1 more source

Smart selective navigator (SSN): enhancing urban winter road maintenance through optimized arc routing with hard turn restrictions

open access: yesInternational Transactions in Operational Research, Volume 33, Issue 5, Page 3580-3597, September 2026.
Abstract This paper introduces a novel heuristic method, the smart selective navigator (SSN), for addressing arc routing problems (ARPs) with a focus on integrating hard turn restrictions in urban winter operations. Addressing a significant gap in existing ARP methodologies, SSN seamlessly incorporates common side constraints, such as vehicle ...
Farhad Baghyari, Jaho Seo
wiley   +1 more source

Decoding the Black Box of Fish Vaccines Efficacy in Basic and Applied Contexts

open access: yesReviews in Aquaculture, Volume 18, Issue 4, September 2026.
ABSTRACT Vaccines are the frontline defense in aquaculture, yet predicting their real‐world performance remains a tricky puzzle. Unlike terrestrial veterinary vaccines, fish vaccines largely operate through “Black Box” processes, where we observe the outcomes but rarely understand the underlying immune mechanisms. Laboratory trials, though informative,
Jiří Kyslík   +2 more
wiley   +1 more source

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