Results 121 to 130 of about 425,158 (263)
Interobserver variability of histopathological assessment in pT1 colorectal carcinoma
Interobserver variability among 20 gastrointestinal pathologists was evaluated on 80 pT1 colorectal carcinoma cases. A pilot phase was followed by a consensus meeting, then a larger concordance study was performed. High interobserver agreement was achieved after consensus for histological grade, lymphovascular invasion, tumour budding, poorly ...
Karmele Saez de Gordoa +24 more
wiley +1 more source
Scat DNA Applications for Low‐Density Carnivore Survey: Techniques, Efficiency and Future Directions
We reviewed 338 studies encompassing mostly Felidae, Canidae and Mustelidae species throughout the world, confirming scat DNA as a reliable genetic source for many applications. The findings here offer guidance for future studies on low‐density carnivores, helping to design cost‐effective research and improving data quality for conservation efforts ...
Marina Elisa de Oliveira +2 more
wiley +1 more source
Skillful Polar WRF Cloud Modeling of a Warm Winter Atmospheric River at the Antarctic Peninsula
Abstract Atmospheric rivers are episodic events that can advect relatively large quantities of moisture to Antarctica, contributing to both disproportionate precipitation and melting events. The Year of Polar Prediction, an international effort to improve weather prediction over the southern polar region, presents an opportunity to study the clouds and
K. M. Hines +9 more
wiley +1 more source
Resolving Convection Doubles Sahel's Contribution to Global Dust Emission During the Monsoon Season
Abstract Current climate models struggle to capture the mean state and variability of dust emissions. This is partially due to their inability to resolve convection, a consequence of their relatively coarse spatial resolution. Via analysis of output from an offline dust emission scheme forced with output from a global storm‐resolving model, we show ...
Tong Ying +5 more
wiley +1 more source
Relapse remains a major challenge in the clinical management of acute myeloid leukemia (AML) and is driven by rare therapy‐resistant leukemia stem cells (LSCs) that reside in specific bone marrow niches.
Talia Velasco‐Hernandez +28 more
doaj +1 more source
Integrated scFv identification and CAR T cell generation for AML targeting in vivo
What's new? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu +13 more
wiley +1 more source
Minimal Evidence of Inflammaging in Naturalistic Chimpanzee Populations
ABSTRACT Objectives Whereas chronic inflammation is a hallmark of aging in many human populations, inflammaging is reduced in groups characterized by frequent physical activity and diets low in processed foods. Since most biomarkers of inflammation require blood sampling, comparative data from our closest primate relatives have been derived from ...
Megan F. Cole +6 more
wiley +1 more source
DNA methylation-associated dysregulation of transfer RNA expression in human cancer
Margalida Rosselló-Tortella +4 more
doaj +1 more source

