Results 21 to 30 of about 90,966 (279)

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

Modeling the separation of water‐in‐oil emulsions in continuously fed gravity settlers using millifluidic experiments

AIChE Journal, EarlyView.
Abstract Emulsion separation remains a persistent challenge in chemical and process industries due to the metastable nature of dispersed droplets. In gravity separators, the overall separation rate is governed by the formation of a densely packed zone (DPZ) of deforming and coalescing droplets that mediates between the dispersed and continuous phases ...
Andrei Zlobin, José Esteban Andino‐Enriquez, Thomas Gouëzec, Maurice Bourrel, Enric Santanach‐Carreras, Nicolas Passade‐Boupat, Laurence Talini, François Lequeux, Pascal Panizza   +8 more
wiley   +1 more source

Divergent leukaemia subclones as cellular models for testing vulnerabilities associated with gains in chromosomes 7, 8 or 18

Scientific Reports, 2021
Haematopoietic malignancies are frequently characterized by karyotypic abnormalities. The development of targeted drugs has been pioneered with compounds against gene products of fusion genes caused by chromosomal translocations.
Michael Maher, Jeannine Diesch, Marguerite-Marie Le Pannérer, Marta Cabezón, Mar Mallo, Sara Vergara, Aleix Méndez López, Alba Mesa Tudel, Francesc Solé, Marc Sorigue, Lurdes Zamora, Isabel Granada, Marcus Buschbeck   +12 more
doaj   +1 more source

A Global Prospective Harmonization Framework for Suicidality, Anhedonia, and Obsessive‐Compulsive Symptoms in Psychiatric Genetic Studies: A Cross‐Continental Study Within the Ancestral Population Network

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT This study aims to prospectively collect harmonized, quantitative, and dimensional psychiatric phenotypes (suicidality, anhedonia, and obsessive‐compulsive symptoms) and information on discrimination, stigma, and unfair treatment in up to 27,500 individuals across diverse ancestries and clinical populations for genetic analysis within the NIMH
Ana M. Diaz‐Zuluaga, Jacey L. Anderberg, Ana M. Ramirez‐Diaz, Andrea Horvath Marques, Catherine E. Rast, Daniel Bustamante, Deborah Jonker, Johanna Valencia‐Echeverry, Joseph Kyebuzibwa, Josselyn S. Muñoz, Kristien van der Walt, Mauricio Castaño Ramirez, Olivia Wootton, Renee M. Frederick, Rocky E. Stroud II, Ruben Gur, Sang Jin Rhee, Shaili C. Jha, Stella Gichuru, Susan Service, Victor I. Reus, Akena Dickens, Carlos Lopez‐Jaramillo, Carrie E. Bearden, Dan J. Stein, Ezra S. Susser, James J. Crowley, Jonathan Flint, Kenneth S. Kendler, Lukoye Atwoli, Michele T. Pato, Nelson B. Freimer, Roel A. Ophoff, Yong Min Ahn, Loes Olde Loohuis, Eric A. Storch, Bizu Gelaye   +36 more
wiley   +1 more source

Estrategias en la construcción de un prototipo como modelo integral en la gestión investigativa orientado hacia el esquema de negocio

Publicaciones e Investigación, 2015
Este artículo muestra los resultados del proyecto Geinve v1.0, el cual busca fortalecer los procesos automatizados de la universidad ECCI, con el apoyo de su grupo de investigación Sistema de Gestión Científica y Tecnología, Sigcienty, y los semilleros ...
Nancy E Ochoa G, Ingrid M Cruz B, Celio E Gil, Cristian Camilo Silva Chaves, Sara Ketherine Grajales B, Leidy Lorena Vergara Vargas, María Paula Perea Díaz, Alonso Páez   +7 more
doaj   +1 more source

Efficient elimination of primary B-ALL cells in vitro and in vivo using a novel 4-1BB-based CAR targeting a membrane-distal CD22 epitope

Journal for ImmunoTherapy of Cancer, 2020
Background There are few therapeutic options available for patients with B-cell acute lymphoblastic leukemia (B-ALL) relapsing as CD19– either after chemotherapy or CD19-targeted immunotherapies.
Pablo Menendez, Pablo Engel, Clara Bueno, Matteo Libero Baroni, Talia Velasco-Hernandez, Heleia Roca-Ho, Francisco Gutierrez-Aguera, Paolo Petazzi, Diego Sánchez-Martínez, Oscar Molina, Paola Ballerini, Narcis Fernandez-Fuentes   +11 more
doaj   +1 more source

Production Country Origin Impact on Soybean Oil Quality

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Previous studies have suggested variability in soybean oil quality depending on geographic origin of the soybeans. In this study, 1035 crude degummed soybean oil (raw oil unrefined except for degumming) samples collected from vessels and crushers over five harvest years (2020–2024) were analyzed for 11 key quality attributes.
Huazhen Liu, Micah Pope, Todd Doehring, Pradeep Kachroo, David Hildebrand   +4 more
wiley   +1 more source

Participantes en eventos populares de ciclismo de montaña en áreas protegidas periurbanas: ¿dónde está el límite?

Apunts: Educación Física y Deportes
En los entornos periurbanos, los eventos deportivos al aire libre, como el ciclismo o las carreras de montaña, suelen llevarse a cabo en espacios naturales y protegidos.
Ricardo Manuel Nogueira Mendes, Carlos Pereira da Silva, Estela Inés Farías-Torbidoni, Teresa Santos   +3 more
doaj   +1 more source

LOS PROCESOS DE ACREDITACIÓN DE LAS CARRERAS DE GRADO DE INGENIERÍA Y AGRONOMÍA. UNA MIRADA SOBRE LA PARTICIPACIÓN DE ACTORES [PDF]

, 2013
Este trabajo es parte de una investigación que se desarrolla en el marco del Proyecto UBACYT 2002010010050611 -dirigido por María Catalina Nosiglia- cuyo objetivo consiste en, por un lado, describir y analizar las políticas de acreditación de las ...
Nosiglia, María Catalina, Polzella, Ángeles, Mulle, Verónica, Zaba, Stella Maris   +3 more
core  

Treatment of a Large Cohort of Childhood Chronic Noninfectious Uveitis in a Multicentric Large Study: Adalimumab Versus Methotrexate as First‐Line Therapy

Arthritis &Rheumatology, EarlyView.
Objective Treatment of childhood chronic idiopathic uveitis (cCIU) is predominantly based on studies in juvenile idiopathic arthritis–associated uveitis and expert opinion. Our aim was to report the treatment outcomes of our cohort of cCIU. Methods Retrospective multicenter study involving the rheumatology and ophthalmology units at Florence, Italy ...
Ilaria Maccora, Catherine Guly, Cinzia de Libero, Giulia Carreras, Athimalaipet V. Ramanan, Gabriele Simonini   +5 more
wiley   +1 more source