Results 91 to 100 of about 164,521 (355)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Current molecular epidemiology of methicillin-resistant Staphylococcus aureus in elderly French people: troublesome clones on the horizon

open access: yesFrontiers in Microbiology, 2016
Objective. In 2015, we conducted at 44 healthcare facilities (HCFs) and 21 nursing homes (NHs) a three-month bloodstream infection (BSI) survey, and a one-day prevalence study to determine the rate of carriage of methicillin-resistant Staphylococcus ...
Claire eRondeau   +8 more
doaj   +1 more source

Duration of Carbapenemase-Producing Enterobacteriaceae Carriage in Hospital Patients

open access: yesEmerging Infectious Diseases, 2020
To determine the duration of carbapenemase-producing Enterobacteriaceae (CPE) carriage, we studied 21 CPE carriers for »1 year. Mean carriage duration was 86 days; probability of decolonization in 1 year was 98.5%, suggesting that CPE-carriers’ status ...
Yin Mo   +13 more
doaj   +1 more source

Pneumococcal carriage in vaccine-eligible children and unvaccinated infants in Lao PDR two years following the introduction of the 13-valent pneumococcal conjugate vaccine.

open access: yesVaccine, 2019
Pneumococcal carriage is a prerequisite for disease, and underpins herd protection provided by pneumococcal conjugate vaccines (PCVs). There are few data on the impact of PCVs in lower income settings, particularly in Asia.
C. Satzke   +15 more
semanticscholar   +1 more source

High levels of recombination among Streptococcus pneumoniae isolates from the Gambia. [PDF]

open access: yes, 2011
We carried out multilocus sequence typing (MLST) on 148 pneumococcal carriage isolates collected from children
Bishop, CJ   +14 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Outbreaks of Kingella kingae Infections in Daycare Facilities

open access: yesEmerging Infectious Diseases, 2014
During the past decade, transmission of the bacterium Kingella kingae has caused clusters of serious infections, including osteomyelitis, septic arthritis, bacteremia, endocarditis, and meningitis, among children in daycare centers in the United States ...
Pablo Yagupsky
doaj   +1 more source

Chlorhexidine and octenidine use, carriage of qac genes, and reduced antiseptic susceptibility in methicillin-resistant Staphylococcus aureus isolates from a healthcare network.

open access: yesClinical Microbiology and Infection, 2019
OBJECTIVES With the widespread use of antiseptics in healthcare facilities for the prevention of methicillin-resistant Staphylococcus aureus (MRSA) transmission, there are concerns for antiseptic tolerance and resistance.
H. Htun   +4 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Carbapenem- and colistin-resistant Enterobacterales in intensive care unit patients in Mediterranean countries, 2019

open access: yesFrontiers in Microbiology
IntroductionThe colonization of patients by carbapenemase-producing Enterobacterales (CPE) has been associated with heightened mortality, especially in vulnerable individuals within intensive care units (ICUs).
Sandra Dos Santos   +16 more
doaj   +1 more source

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