Results 211 to 220 of about 136,459 (295)

The Effect of Head-Forward Posture on Lower Neck Loads and Dislocation Risk in Head-First Impact: A Computational and Experimental Investigation. [PDF]

JOR Spine
Mongiardini M, Cronin D, Quarrington RD.
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Carriage rate of CPE, ESBL-producing coliforms and MRSA in community settings in Suriname. [PDF]

JAC Antimicrob Resist
Rozemond CM, Adhin MR, Williams W, De Greeff SC, Van Duijkeren E, Vreden SG, Mawie FT, Ijzerman E, Hordijk J, Van Dissel JT.   +9 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Prevalence, Serotype Distribution, and Risk Factors Associated With <i>Streptococcus pneumoniae</i> Carriage in Older Adults in Denmark, 2019-2022. [PDF]

Open Forum Infect Dis
Tinggaard M, Slotved HC, Petersen RF, Hovmand N, Benfield T.   +4 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Correction: Chronic exposure to intestinal parasites and bacterial enteropathogens among children in rural Madagascar: Implications for asymptomatic carriage and co-infections. [PDF]

PLoS Negl Trop Dis
Wilczyńska W, Kasprowicz D, Korzeniewski K.   +2 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Molecular Epidemiology and Conjugative Transferability of <i>bla</i>_OXA-48/<i>bla</i>_NDM-1 Co-Occurrence in Extensively Drug-Resistant <i>Klebsiella pneumoniae</i> from Egyptian Tertiary Care Hospitals. [PDF]

Pathogens
El-Sayed Ahmed MAE, Elghopashy AEI, Ragab YM, El-Lakany RR, Abdelrahman D, Omar AA, Goda RM.   +6 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source