Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Are high residual chlorhexidine skin concentrations associated with improved clinical outcomes? Lessons from the CLEAR trial. [PDF]
Khoja R +7 more
europepmc +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Genomic and statistical models to characterize <i>Streptococcus pneumoniae</i> transmission patterns in Malawi. [PDF]
Cave R +14 more
europepmc +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Lipidated Protein D vaccination elicits humoral and cellular responses and protects mice against challenge with non-typeable <i>Haemophilus influenzae</i>. [PDF]
Thayer TC +6 more
europepmc +1 more source
Challenges and insights in self-swab surveillance for asymptomatic Streptococcus pyogenes carriage. [PDF]
Enkel SL, Wong B, Bowen AC.
europepmc +1 more source
Screening for extended spectrum beta-lactamase-producing organisms in colorectal and genitourinary tract surgeries at the Lebanese American University Medical Center-Rizk Hospital. [PDF]
Farra A +7 more
europepmc +1 more source
Effects of load carriage methods on fall risk and gait variability during stair ascent: a functional data analysis approach. [PDF]
Zhang X +11 more
europepmc +1 more source

