Results 131 to 140 of about 1,197,586 (303)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Motor carrier safety

open access: yes, 2007
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on Nov.

core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

FMCSA Safety Program Effectiveness Measurement: Carrier Intervention Effectiveness Model, Version 1.3\u2014Report for FY 2019 Interventions [Analysis Brief]

open access: yes
The Federal Motor Carrier Safety Administration (FMCSA), in cooperation with the John A. Volpe National Transportation Systems Center (Volpe), uses a quantitative model called the Carrier Intervention Effectiveness Model (CIEM) to measure the ...
United States. Department of Transportation. Federal Motor Carrier Safety Administration
core  

Ultrafast directional hot carrier transfer in bilayer perovskite heterojunctions. [PDF]

open access: yesNat Commun
Liu S   +12 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

John Carrier Interview

open access: yes, 2016
This interview of john Carrier is a part of the HIV/AIDS Oral History Project which interviewed individuals in southeast Minnesota and the Winona, Minnesota area about the HIV/AIDs crisis in the 1980s and 1990s. The student interviewers are Latasha Bell,
Carrier, John
core  

ARTICLES, REPORTS AND SPEECHES, 1998-2008 - Lectures - Carrier-Johnson Lecture, 2004

open access: yes, 2016
Lecture from Carrier-Johnson Architects on September 17, 2004.http://deepblue.lib.umich.edu/bitstream/2027.42/118097/2/39015094711101.mp4http://deepblue.lib.umich.edu/bitstream/2027.42/118097/3/39015094711101 ...
University of Michigan. A. Alfred Taubman College of Architecture and Urban Planning
core   +1 more source

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