Results 141 to 150 of about 1,197,586 (303)
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The demon and the darling of the gods; a drama, by Wilbur Carrier ...
3 p.
Carrier, J. Wilbur.
core
High out-of-plane piezoelectric response in Janus SeWZH (Z = N, P, As) semiconductors: a first-principles prediction. [PDF]
Kartamyshev AI +6 more
europepmc +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Photon cascade engineering in AgCdF<sub>3</sub>/Cu<sub>2</sub>GeSiS<sub>4</sub> dual-absorber solar cells: from spectral complementarity to device excellence. [PDF]
Hossain MF +6 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
NbN Broadband Plasmonic Absorbers for Efficient Hot-Carrier Injection Toward Improved Solar-to-Hydrogen Conversion. [PDF]
Peng TY +11 more
europepmc +1 more source

