Results 141 to 150 of about 757,612 (267)
Every Picture Tells a Story: Visual Alternatives to Oral Tradition in Ponam Society [PDF]
James Carrier, Achsah Carrier
doaj
Quantum-modified photo-thermoelastic wave propagation in semiconductors with temperature-dependent thermal conductivity. [PDF]
Alshalhoub S +5 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Precise Reproductive Counseling Enabled by Long-Read Sequencing in a Case of a <i>F8</i> Intron 1 Inversion and Duplication. [PDF]
Yan Y, Jin P, Xu L, Ma Y, Dong M.
europepmc +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Configuration-Selective Photocurrent Enhancement Induced by Static Domain Walls in Two-Dimensional Ferroelectric In<sub>2</sub>Se<sub>3</sub>. [PDF]
Xu N, Xu Y.
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source

