Results 201 to 210 of about 1,197,586 (303)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Mn Doping-Induced Charge-Carrier Redistribution in Co₃O₄ for Enhanced CO₂ Photoreduction Toward CH₄ with H₂O. [PDF]

Molecules
Zhou G, Shangguan W, Wang X, Wang S, Li K, Li S, Ma Y, Meng S, Chen S.   +8 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Acyl carrier protein is essential for apicoplast biogenesis in malaria parasites independent of fatty acid synthesis. [PDF]

Elife
Geher SWR, Falekun S, Pita-Aquino JN, Swift RP, Okada M, Jami-Alahmadi Y, Wohlschlegel JA, Prigge ST, Sigala PA.   +8 more
europepmc   +1 more source

Diphtheria Carriers

American Journal of Public Health and the Nations Health, 1929
openaire   +3 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

FXI Deficiency Found on Expanded Carrer Screening: A Quandry in Routine Obstetric Management

Journal of Scientific Innovation in Medicine, 2019
Melissa Chu Lam, Justine Viola, Dyese Taylor, Farrah Hussain, Jessica Overbey, Stephanie Pan, David Cole, Barak Rosenn   +7 more
doaj   +1 more source

Hydrogen Carrier Gas Method Translation in Comprehensive Two-Dimensional Gas Chromatography for Sustainable Nontargeted Analysis. [PDF]

Anal Chem
Fisher KM, Macturk EL, Perrault Uptmor KA.   +2 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source