Bandwidth correction of Swarm GPS carrier phase observations for improved orbit and gravity field determination. [PDF]
GPS Solut, 2021 Schreiter L +5 more
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Influence of Precise Products on the Day-Boundary Discontinuities in GNSS Carrier Phase Time Transfer. [PDF]
Sensors (Basel), 2021 Zhang X +6 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Classification of Cross-Country Ski Skating Sub-Technique Can Be Automated Using Carrier-Phase Differential GNSS Measurements of the Head's Position. [PDF]
Sensors (Basel), 2021 Gløersen Ø, Gilgien M.
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Antisaturation Carrier Tracking Technique for Ground‐Based Positioning Systems
IET Radar, Sonar & NavigationAs an alternative to global navigation satellite systems (GNSS), ground‐based positioning systems (GBPS) can achieve high‐precision positioning based on carrier phase measurements in GNSS‐denied environments.
Hongchuan Zhang, Zheng Yao, Mingquan Lu
doaj +1 more source
Reduced sampling rate Kalman filters for carrier phase and frequency offset tracking in 200 Gbps 16 QAM coherent communication system. [PDF]
Sci Rep, 2021 Sharma S, Krishnamurthy PK.
europepmc +1 more source