Results 121 to 130 of about 404,297 (306)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Phase sensitive parametric amplifiers and their applications

open access: yes, 2012
Phase sensitive amplification (PSA) is a remarkably powerful tool if implemented correctly - it allows amplification with a noise figure lower than quantum mechanics normally dictates, and also allows the development of systems that coherently process ...
Kakande, Joseph
core  

Analysis of Multi-Antenna GNSS Receiver Performance under Jamming Attacks

open access: yesSensors, 2016
Although antenna array-based Global Navigation Satellite System (GNSS) receivers can be used to mitigate both narrowband and wideband electronic interference sources, measurement distortions induced by array processing methods are not suitable for high ...
Niranjana Vagle   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Modeling and Quantitative Analysis of GNSS/INS Deep Integration Tracking Loops in High Dynamics

open access: yesMicromachines, 2017
To meet the requirements of global navigation satellite systems (GNSS) precision applications in high dynamics, this paper describes a study on the carrier phase tracking technology of the GNSS/inertial navigation system (INS) deep integration system ...
Yalong Ban   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Viterbi-Viterbi Carrier Phase Estimation for Multi-Ring $M$-APSK With Wiener Carrier Phase Noise and Its Performance

open access: yesIEEE Photonics Journal
High-order modulations are currently widely used in optical communications to increase the data rate. However, due to the existence of laser phase noise, the performance of high-order modulated systems will be greatly degraded.
Qian Wang   +5 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

GPS Based Attitude Determination for the Flying Laptop Satellite

open access: yes, 2007
This paper introduces the GPS based attitude determination system (GENIUS) onboard the university small satellite Flying Laptop. The attitude determination algorithm which is based on a Kalman Filter and processes single differences of the C/A-code and ...
Gillmayer, Georg   +5 more
core  

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