Results 121 to 130 of about 559,012 (379)
Functional heterogeneity of ubiquitin carrier proteins.
Journal of Biological Chemistry, 1985 In the formation of covalent ubiquitin-protein conjugates that occurs during ATP- and ubiquitin-dependent proteolysis in reticulocyte extracts, ubiquitin (Ub) is activated to a thiol ester of the activating enzyme E1 (via the Ub carboxyl terminus), transferred to low-molecular weight "carrier proteins" (E2s) to form E2-Ub thiol esters, and then ...
C M Pickart, I A Rose
openaire +4 more sources
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
The chemistry and use of cellulose derivatives for the study of biological systems [PDF]
Cellulose chemistry and applications as carrier for proteins, polymers, and organic ...
Weetall, H. H., Weliky, N.
core +1 more source
Molecular Oncology, EarlyView.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
Glassy protein dynamics and gigantic solvent reorganization energy of plastocyanin [PDF]
arXiv, 2007 We report the results of Molecular Dynamics simulations of electron transfer activation parameters of plastocyanin metalloprotein involved as electron carrier in natural photosynthesis. We have discovered that slow, non-ergodic conformational fluctuations of the protein, coupled to hydrating water, result in a very broad distribution of donor-acceptor ...
arxiv
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
EVIDENCE FOR A 12 kDa "CARRIER PROTEIN" FOR NATRIURETIC HORMONE
Frontiers in Endocrinology, 2014 The search for the elusive natriuretic hormone continues. In this review evidence is presented that isolating the carrier protein for natriuretic hormone is a necessary first step before splitting off the final hormone.
Harvey Craig Gonick
doaj +1 more source
How proteins are transported into mitochondria [PDF]
, 1981 Most mitochondrial polypeptides are synthesized outside the organelle as precursors which are usually larger than the ‘mature’ polypeptides found within mitochondria.
Neupert, Walter, Schatz, Gottfried
core +1 more source
Acta Dermato-Venereologica, 1978 Contact hypersensitivity to picrylchloride was induced in guinea pigs by the subcutaneous injection of heteroantigenic components which were isolated by antibody immunoadsorbent from soluble epidermal proteins of picrylchloride painted guinea pigs.
S, Miyagawa, N, Miyagawa
openaire +2 more sources
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source