Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency [PDF]
Frontiers in Physiology, 2017 Coenzyme Q is a lipid that participates to important physiological functions. Coenzyme Q is synthesized in multiple steps from the precursor 4-hydroxybenzoic acid.
Fabien Pierrel
exaly +4 more sources
Physiological metabolic analysis and process optimization of hypoxia in promoting coenzyme Q10 biosynthesis and accumulation in Rhodobacter sphaeroides HY01 [PDF]
Synthetic and Systems BiotechnologyCoenzyme Q10 fermentation by Rhodobacter sphaeroides (R. sphaeroides) is highly aerobic. However, its biosynthesis and accumulation are paradoxically induced under hypoxic conditions.
Bo Li +9 more
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Inhibition of Histone Lysine Acetyltransferases by Coenzyme A Analogs [PDF]
MoleculesHistone lysine acetylation is a widespread posttranslational modification, essential for vital functions in eukaryotic organisms. Histone lysine acetyltransferases (KATs) employ acetyl-coenzyme A as a universal acetyl donor for acetylation of lysine ...
Faidra Voukia +3 more
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Pantothenic acid – a scoping review for Nordic Nutrition Recommendations 2023
Food & Nutrition Research, 2023 Pantothenic acid, also referred to as vitamin B5, is a water-soluble vitamin that has essential functions in the body as a component of coenzyme A (CoA) and acyl carrier protein (ACP).
Riitta Freese +2 more
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A conserved oxalyl-coenzyme A decarboxylase in oxalate catabolism
Plant Signaling & Behavior, 2022 The ability to biosynthesize oxalic acid can provide beneficial functions to plants; however, uncontrolled or prolonged exposure to this strong organic acid results in multiple physiological problems.
Ninghui Cheng +4 more
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eLife, 2021 TMEM120A, also named as TACAN, is a novel membrane protein highly conserved in vertebrates and was recently proposed to be a mechanosensitive channel involved in sensing mechanical pain.
Jing Xue +8 more
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Frontiers in Microbiology, 2021 Mycoplasmas are responsible for a wide range of disease states in both humans and animals, in which their parasitic lifestyle has allowed them to reduce their genome sizes and curtail their biosynthetic capabilities.
Tertius Alwyn Ras +2 more
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The pathophysiology of leg cramping during dialysis and the use of carnitine in its treatment
Physiological Reports, 2021 Leg cramping is a common side effect of hemodialysis, and this is frequently treated by the administration of carnitine, but this is not effective in every patient. Alkalosis is a key component of the etiology of leg cramping during hemodialysis sessions.
Akira Takahashi
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The Role of Coenzyme Q10 against Cyclosporine-A Induced Cardiotoxicity in Adult Male Albino Rats (Histological and Toxicological Study) [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2013 Cyclosporine-A (CsA) has a potent immunosuppressive activity and is commonly used as anti-rejection drug after organ transplantation and for treatment of some autoimmune diseases. Several toxic effects on the cardiovascular system have been reported with
Ibrahim Awwad +3 more
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Oxalate-silica gel thin-layer system for free 2-hydroxy fatty acids and for fatty acyl coenzyme A
Journal of Lipid Research, 1972 The 2-hydroxy fatty acids tend to yield streaks in thin-layer chromatography on silica gel plates. If potassium oxalate is included with binder-free silica gel, good spots are obtained.
M. David Ullman, Norman S. Radin
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