Results 11 to 20 of about 148,184 (310)
The metabolism of coenzyme A and control of its synthesis are reviewed. Pantothenate kinase is an important rate-controlling enzyme in the synthetic pathway of all tissues studied and appears to catalyze the flux-generating reaction of the pathway in ...
J. D. Robishaw, J. R. Neely
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Iso-coenzyme A is an isomer of coenzyme A in which the monophosphate is attached to the 2'-carbon of the ribose ring. Although iso-CoA was first reported in 1959 (Moffatt, J. G., and Khorana, H. G. (1959) J. Am. Chem. Soc. 81, 1265-1265) to be a by-product of the chemical synthesis of CoA, relatively little attention has been focused on iso-CoA or on ...
Kristi L, Burns +4 more
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Biosynthesis of food constituents: Vitamins. 2. Water-soluble vitamins: Part 1 - a review
This review article gives a survey of the generally accepted biosynthetic pathways that lead to water-soluble vitamins in microorganisms, plants and some animals.
Jan Velíšek, Karel Cejpek
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Atherosclerosis and Coenzyme Q10 [PDF]
Atherosclerosis is the most common cause of cardiac deaths worldwide. Classically, atherosclerosis has been explained as a simple arterial lipid deposition with concomitant loss of vascular elasticity. Eventually, this condition can lead to consequent blood flow reduction through the affected vessel.
Juan M. Suárez-Rivero +10 more
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Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection
Coenzyme A (CoA) and acetyl-coenzyme A (acetyl-CoA) play essential roles in cell energy metabolism. Dysregulation of the biosynthesis and functioning of both compounds may contribute to various pathological conditions.
Yevgeniya I. Shurubor +7 more
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Auxotrophic Selection Strategy for Improved Production of Coenzyme B12 in Escherichia coli
Summary: The production of coenzyme B12 using well-characterized microorganisms, such as Escherichia coli, has recently attracted considerable attention to meet growing demands of coenzyme B12 in various applications. In the present study, we designed an
Myung Hyun Noh +4 more
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Investigation of coenzyme Q10 status, serum amyloid-β, and tau protein in patients with dementia
ObjectivesDementia is an oxidative stress-related disease. Coenzyme Q10 is a nutrient that occurs naturally in the human body and acts as an antioxidant.
Po-Sheng Chang +10 more
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Our study aimed to develop a self-microemulsifying drug delivery system for the poorly aqueous-soluble drug Coenzyme Q10, to improve the dissolution and the oral bioavailability.
Thapa Chhitij +11 more
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Background AarF domain-containing kinase 4 (ADCK4)-associated glomerulopathy is a mitochondrial nephropathy caused by mutations in the ADCK4 gene, which disrupt coenzyme Q10 biosynthesis.
Yan Zhang +8 more
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Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family
By consensus, the acyl-CoA synthetase (ACS) community, with the advice of the human and mouse genome nomenclature committees, has revised the nomenclature for the mammalian long-chain acyl-CoA synthetases.
Douglas G. Mashek +19 more
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