Results 41 to 50 of about 114,066,372 (194)

The effect of the antioxidant, Coenzyme Q, on Coco-2 colon cells treated with iron to reduce lipid peroxidation [PDF]

open access: yes, 2002
Plan BThe objective of this study was to determine if Coenzyme Q10 (also known as ubiquinone) acting as an antioxidant, would protect against free radical damage to cell membranes that can cause cancer.
Johanknecht, Viva M.
core  

Cholesterol suppresses antimicrobial effect of statins [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2015
Objective(s):Isoprenoid biosynthesis is a key metabolic pathway to produce a wide variety of biomolecules such as cholesterol and carotenoids, which target cell membranes.
Mohammad Reza Haeri   +3 more
doaj  

The role of Coenzyme Q10 in statin-associated myopathy [PDF]

open access: yes, 2009
Statins, or 3-hydroxyl-3-methylglutaryl coenzyme HMG-CoA reductase inhibitors,\ud are cholesterol-lowering drugs which are frequently used in the primary and secondary\ud prevention of coronary artery disease. Current research and recommendations support\
Kalra, Dr Sanjay
core  

Effect of iron and silver nanoparticles on coenzyme Q10 production by Gluconobacter japonicus FM10

open access: yesIranian Journal of Microbiology, 2020
Background and Objectives: Coenzyme Q10 is an anti-aging agent whose demand is increasing progressively. There are various strategies used for increasing coenzyme Q10 production by microorganisms.
Foozieh Moghadami, Ramin Hosseini
doaj   +1 more source

NME4 mediates metabolic reprogramming and promotes nonalcoholic fatty liver disease progression

open access: yesEMBO Reports, 2023
Nonalcoholic fatty liver disease (NAFLD) is mainly characterized by excessive fat accumulation in the liver, and it is associated with liver-related complications and adverse systemic diseases.
Shaofang Xie   +5 more
doaj   +1 more source

Conformational switch upon substrate binding informs the rational design of CCoAOMT enzymes

open access: yesScientific Reports
Poplar is a deciduous tree belonging to the willow family, whose wood has the characteristics of light texture and toughness. It can be used to produce pulp, and is one of the main raw materials in the paper industry. A large amount of lignin is produced
Yujie Cao   +10 more
doaj   +1 more source

Knock-down of pantothenate kinase 2 severely affects the development of the nervous and vascular system in zebrafish, providing new insights into PKAN disease

open access: yesNeurobiology of Disease, 2016
: Pantothenate Kinase Associated Neurodegeneration (PKAN) is an autosomal recessive disorder with mutations in the pantothenate kinase 2 gene (PANK2), encoding an essential enzyme for Coenzyme A (CoA) biosynthesis.
Daniela Zizioli   +10 more
doaj   +1 more source

THE IMPACT OF CARDIOVASCULAR AND BRONCHOPULMONARY DISEASES ON COENZYME Q10 PLASMA CONCENTRATION

open access: yesСеченовский вестник, 2019
Introduction. Coenzyme Q10 plays an important role in the human body. Its main function is not only the transfer of electrons in the mitochondrial respiratory chain for the ATP synthesis, but it is also one of the most powerful antioxidants in the body ...
V. I. Zozina   +4 more
doaj   +1 more source

Coenzyme-Q10 és obesitas kapcsolata

open access: yes, 2016
Az obesitas napjaink egyik legnagyobb problémáját jelentő betegsége, mely egyre több embert érint. Napjainkig is rendkívül nehéz feladat az obesitas és kísérő betegségeinek kezelése, ezért folyamatos kutatasok folynak a lehetséges kiváltó okok, illetve ...
Kádár, Emese Lenke
core  

4′‐Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN

open access: yesEMBO Molecular Medicine, 2019
Pantothenate kinase‐associated neurodegeneration (PKAN) is an inborn error of CoA metabolism causing dystonia, parkinsonism, and brain iron accumulation.
Suh Young Jeong   +22 more
doaj   +1 more source

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