Results 51 to 60 of about 114,066,372 (194)
Journal of Lipid Research, 2008 The hepatic enzyme bile acid CoA:amino acid N-acyltransferase (BAT) catalyzes the formation of amino acid-conjugated bile acids. In the present study, protein carbonylation of BAT, consistent with modification by reactive oxygen species and their ...
E.M. Shonsey +6 more
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The phosphatase Ptc7 induces coenzyme Q biosynthesis by activating the hydroxylase coq7 in yeast
, 2013 The study of the components of mitochondrial metabolism has potential benefits for health span and lifespan because the maintenance of efficient mitochondrial function and antioxidant capacity is associated with improved health and survival.
Padilla, Sergio +6 more
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Photochromic Coenzyme Q Derivatives: Switching Redox Potentials with Light [PDF]
, 2017 Coenzyme Q is an important redox cofactor involved in a variety of cellular processes, and thus found in several cell compartments. We report a photochromic derivative of coenzyme Q that combines the molecular structures of the redox active cofactor and ...
Andrea C. Kneuttinger +8 more
core +1 more source
, 2015 Objective: To determine if coenzyme Q10 alleviates fatigue in the late-onset sequelae of poliomyelitis. Design: Parallel-group, randomized, placebo-controlled trial.
Cooke, Marie +10 more
core +1 more source
Coenzyme Q10: From Fact to Fiction
, 2015 There is a growing interest in coenzyme Q10 (CoQ10) and its involvement in many aspects of daily living including physical and mental health, energy, aging, stress, skin care and exercise. This book aims to highlight our current understanding of CoQ10 in
Hargreaves, April, Hargreaves, Iain
core +3 more sources
CoA‐dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases
EMBO Molecular Medicine, 2019 PKAN, CoPAN, MePAN, and PDH‐E2 deficiency share key phenotypic features but harbor defects in distinct metabolic processes. Selective damage to the globus pallidus occurs in these genetic neurodegenerative diseases, which arise from defects in CoA ...
Roald A Lambrechts +10 more
doaj +1 more source
Coenzyme A and its derivatives: renaissance of a textbook classic
, 2014 In 1945, Fritz Lipmann discovered a heat-stable cofactor required for many enzyme-catalysed acetylation reactions. He later determined the structure for this acetylation coenzyme, or coenzyme A (CoA), an achievement for which he was awarded the Nobel ...
Theodoulou, Frederica L. +8 more
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Effects of myosin heavy chain (MHC) plasticity induced by HMGCoA-reductase inhibition on skeletal muscle functions. [PDF]
, 2011 The rate-limiting step of cholesterol biosynthetic pathway is catalyzed by 3-hydroxy-3-methylglutaryl coenzyme reductase (HGMR), whose inhibitors, the statins, widely used in clinical practice to treat hypercholesterolemia, often cause myopathy, and ...
Moreno, Sandra +34 more
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Effects of Coenzyme Q10 on LDL Oxidation In vitro
Acta Medica Iranica, 2013 Coenzyme Q10, a lipid soluble benzoquinone, has excellent antioxidant and membrane stabilizing properties in the cardiac tissue. The present study investigated the effects of coenzyme Q10 on in vitro LDL oxidation quantitavely.
Hiroshi Mabuchi +3 more
doaj +2 more sources
ETFDH mutation involves excessive apoptosis and neurite outgrowth defect via Bcl2 pathway
Scientific ReportsThe most common mutation in southern Chinese individuals with late-onset multiple acyl-coenzyme A dehydrogenase deficiency (MADD; a fatty acid metabolism disorder) is c.250G > A (p.Ala84Thr) in the electron transfer flavoprotein dehydrogenase gene (ETFDH)
Chuang-Yu Lin +5 more
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