Results 71 to 80 of about 129,225 (257)
4′‐Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN
EMBO Molecular Medicine, 2019 Pantothenate kinase‐associated neurodegeneration (PKAN) is an inborn error of CoA metabolism causing dystonia, parkinsonism, and brain iron accumulation.
Suh Young Jeong +22 more
doaj +1 more source
Journal of Lipid Research, 2008 The hepatic enzyme bile acid CoA:amino acid N-acyltransferase (BAT) catalyzes the formation of amino acid-conjugated bile acids. In the present study, protein carbonylation of BAT, consistent with modification by reactive oxygen species and their ...
E.M. Shonsey +6 more
doaj +1 more source
CoA‐dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases
EMBO Molecular Medicine, 2019 PKAN, CoPAN, MePAN, and PDH‐E2 deficiency share key phenotypic features but harbor defects in distinct metabolic processes. Selective damage to the globus pallidus occurs in these genetic neurodegenerative diseases, which arise from defects in CoA ...
Roald A Lambrechts +10 more
doaj +1 more source
Effects of Coenzyme Q10 on LDL Oxidation In vitro
Acta Medica Iranica, 2013 Coenzyme Q10, a lipid soluble benzoquinone, has excellent antioxidant and membrane stabilizing properties in the cardiac tissue. The present study investigated the effects of coenzyme Q10 on in vitro LDL oxidation quantitavely.
Hiroshi Mabuchi +3 more
doaj +2 more sources
ETFDH mutation involves excessive apoptosis and neurite outgrowth defect via Bcl2 pathway
Scientific ReportsThe most common mutation in southern Chinese individuals with late-onset multiple acyl-coenzyme A dehydrogenase deficiency (MADD; a fatty acid metabolism disorder) is c.250G > A (p.Ala84Thr) in the electron transfer flavoprotein dehydrogenase gene (ETFDH)
Chuang-Yu Lin +5 more
doaj +1 more source
Neurobiology of Disease, 2005 Neuronal cells depend on mitochondrial oxidative phosphorylation for most of their energy needs and therefore are at a particular risk for oxidative stress.
M. Somayajulu +5 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Antioxidants, 2018 The study aims to examine the effects of coenzyme Q10, (a bioenergetic antioxidant), on the indexes of left ventricular remodeling, oxidative damage, and angiotensin-converting enzyme (ACE) level after acute myocardial infarction (AMI) with left ...
Ram B. Singh +3 more
doaj +1 more source
, 2008 Citation: 'coenzyme' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C01126 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +2 more sources