Results 1 to 10 of about 96,183 (271)
Drug Delivery, 2022 Our study aimed to develop a self-microemulsifying drug delivery system for the poorly aqueous-soluble drug Coenzyme Q10, to improve the dissolution and the oral bioavailability.
Thapa Chhitij +11 more
doaj +2 more sources
Coenzyme Q10 and Obesity: An Overview. [PDF]
Antioxidants (Basel)There is evidence for the involvement of mitochondrial dysfunction, oxidative stress, ferroptosis, and inflammation in the pathogenesis of obesity. This, in turn, indicates a novel potential therapeutic role for supplemental coenzyme Q10 (CoQ10) in the management of obesity, due to the role of CoQ10 in promoting normal mitochondrial function, as an ...
Mantle D, Kozhevnikova S, Larsen S.
europepmc +6 more sources
Nutrition Journal, 2022 Background Metabolic syndrome (MetS) as a cluster of conditions including hyperlipidemia, hypertension, hyperglycemia, insulin resistance, and abdominal obesity is linked to cardiovascular diseases and type 2 diabetes.
Abbas Ali Sangouni +4 more
doaj +2 more sources
Antioxidants, 2022 The aim of this study was to explore the use of coenzyme Q10 and skeletal muscle protein biomarkers in the diagnosis of sarcopenia. Subjects with or without sarcopenia were recruited.
Chi-Hua Yen +3 more
doaj +2 more sources
Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review [PDF]
Journal of International Medical ResearchObjective This study aimed to investigate whether coenzyme Q10 is effective in preventing exercise-induced oxidative stress and muscle damage. Methods Fourteen randomized controlled studies examining the effects of supplementation with coenzyme Q10 ...
Yangqi Zhang +4 more
doaj +2 more sources
Methodist DeBakey cardiovascular journal, 2020 Coenzyme Q10 (CoQ10) is among the most widely used dietary and nutritional supplements on the market. CoQ10 has several fundamental properties that may be beneficial in several clinical situations. This article reviews the pertinent chemical, metabolic, and physiologic properties of CoQ10 and the scientific data and clinical trials that address its use
Joseph Katzinger +2 more
+5 more sources
Investigation of coenzyme Q10 status, serum amyloid-β, and tau protein in patients with dementia
Frontiers in Aging Neuroscience, 2022 ObjectivesDementia is an oxidative stress-related disease. Coenzyme Q10 is a nutrient that occurs naturally in the human body and acts as an antioxidant.
Po-Sheng Chang +10 more
doaj +1 more source
Neuroprotective effects of coenzyme Q10 on neurological diseases: a review article
Frontiers in Neuroscience, 2023 Neurological disorders affect the nervous system. Biochemical, structural, or electrical abnormalities in the spinal cord, brain, or other nerves lead to different symptoms, including muscle weakness, paralysis, poor coordination, seizures, loss of ...
Shokufeh Bagheri +6 more
semanticscholar +1 more source
Primary Coenzyme Q10 Deficiency: An Update
Antioxidants, 2023 Coenzyme Q10 (CoQ10) has a number of vital functions in all cells, both mitochondrial and extra-mitochondrial. In addition to its key role in mitochondrial oxidative phosphorylation, CoQ10 serves as a lipid soluble antioxidant and plays an important role
D. Mantle +3 more
semanticscholar +1 more source
BMC Nephrology, 2021 Background AarF domain-containing kinase 4 (ADCK4)-associated glomerulopathy is a mitochondrial nephropathy caused by mutations in the ADCK4 gene, which disrupt coenzyme Q10 biosynthesis.
Yan Zhang +8 more
doaj +1 more source