Results 31 to 40 of about 51,495 (221)

Substantiation of approaches to the correction of lipid metabolism disorders and non-alcoholic fatty liver disease in children with exogenous obesity

Ожирение и метаболизм, 2022
BACKGROUND: According to the involvement of oxidative stress in the pathogenesis of obesity, the plasma level of coenzyme q10 in the correlation relationship with lipid metabolism disorders and functional liver state is of interest to study.AIM ...
O. V. Povarova, E. A. Gorodetskaya, O. Y. Kulyak, A. N. Demyanenko, I. L. Alimova, E. I. Kalenikova, O. S. Medvedev   +6 more
doaj   +1 more source

Coenzyme q10: koenzim q10

Ankara Universitesi Eczacilik Fakultesi Dergisi, 2005
Coenzyme Q10 (CoQ10) is an essential cofactor of the electron transport chain which plays a pivotal role to supply energy for chemical reactions in the body, and a lipophilic antioxidant component of the lipid membranes that surround all cells and the various organelles such as microsomes and mitochondria.
A. Selen GÜRKAN, Oya BOZDAĞ DÜNDAR
openaire   +1 more source

Coenzyme Q10 status, glucose parameters, and antioxidative capacity in college athletes

Journal of the International Society of Sports Nutrition, 2020
Background Glycemia is related to energy production during exercise. Coenzyme Q10 is an antioxidant that participates in adenosine triphosphate synthesis in mitochondria.
Chien-Chang Ho, Ching-Yu Tseng, Hung-Wun Chen, Yi-Wen Chiu, Ming-Chih Tsai, Po-Sheng Chang, Ping-Ting Lin   +6 more
doaj   +1 more source

Neuroprotective effect of hesperidin and its combination with coenzyme Q10 on an animal model of ketamine-induced psychosis: behavioral changes, mitochondrial dysfunctions, and oxidative stress

Future Journal of Pharmaceutical Sciences, 2022
Background Psychosis is a complex mental illness divided by positive symptoms, negative symptoms, and cognitive decline. Clinically available medicines are associated with some serious side effects which limit their use.
Naresh Kumar, Monu Yadav, Anil Kumar, Monika Kadian, Sunil Kumar   +4 more
doaj   +1 more source

Молекулярная фармакология коэнзима Q10 в контексте лечения гиперлипидемических состояний [PDF]

, 2023
Background. Therapy of hyperlipidemia with synthetic statin drugs is characterized by a number of side effects. In particular, statin-dependent myopathy occurs as a result of statin inhibition of biosynthesis of cofactor coenzyme Q10 (CoQ10), which plays
O. A. Gromova, И. Ю. Торшин, О. А. Громова, I. Yu. Torshin   +3 more
core   +1 more source

Physiological metabolic analysis and process optimization of hypoxia in promoting coenzyme Q10 biosynthesis and accumulation in Rhodobacter sphaeroides HY01

Synthetic and Systems Biotechnology
Coenzyme Q10 fermentation by Rhodobacter sphaeroides (R. sphaeroides) is highly aerobic. However, its biosynthesis and accumulation are paradoxically induced under hypoxic conditions.
Bo Li, Yan Ge, Li Fu, Huanan Guo, Ali Mohsin, Junming Li, Jiequn Wu, Biqin Chen, Yingping Zhuang, Zejian Wang   +9 more
doaj   +1 more source

Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials

BMC Cardiovascular Disorders, 2017
Background The therapeutic efficacy of coenzyme Q10 on patients with cardiac failure remains controversial. We pooled previous clinical studies to re-evaluate the efficacy of coenzyme Q10 in patients with cardiac failure.
Li Lei, Yan Liu
doaj   +1 more source

In vitro evaluation of coenzyme Q10 on primary fibroblast culture

Majalah Kedokteran Gigi Indonesia, 2023
Chronic inflammation in periodontitis results in continuous production of Reactive Oxygen Species (ROS), so the levels are excessive, causing destruction of the gingiva, periodontal ligament, and alveolar bone through a variety of mechanisms including ...
Dahlia Herawati
doaj   +1 more source

Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation

Health Technology Assessment, 2022
Background: Chronic heart failure is a debilitating condition that accounts for an annual NHS spend of £2.3B. Low levels of endogenous coenzyme Q10 may exacerbate chronic heart failure. Coenzyme Q10 supplements might improve symptoms and slow progression.
Lindsay Claxton, Mark Simmonds, Lucy Beresford, Richard Cubbon, Mark Dayer, Stephen S Gottlieb, Nick Hartshorne-Evans, Bruce Kilroy, Alexis Llewellyn, Claire Rothery, Sahar Sharif, Jayne F Tierney, Klaus K Witte, Kath Wright, Lesley A Stewart   +14 more
doaj   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source