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The prevalence of dyslipidemia is high. It is usually treated with statins which inhibit HMG-CoA reductase and also coenzyme Q10 synthesis. This may lead to muscle pain. The question whether coenzyme Q10 replacement treatment helps to improve these muscle symptoms has been evaluated in a prospective study.
openaire +2 more sources
THE IMPACT OF CARDIOVASCULAR AND BRONCHOPULMONARY DISEASES ON COENZYME Q10 PLASMA CONCENTRATION
Introduction. Coenzyme Q10 plays an important role in the human body. Its main function is not only the transfer of electrons in the mitochondrial respiratory chain for the ATP synthesis, but it is also one of the most powerful antioxidants in the body ...
V. I. Zozina +4 more
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Effect of Black Sesame Oil Lecithin Solution on Bone Metabolism in Naturally Growing Aged Mice
To observe the effect of black sesame oil lecithin solution on bone metabolism in naturally grown aging mice and compare with vitamin E.8-month-old SPF Kunming mice were randomly divided into normal saline group (NS group),vitamin E group (VE group ...
LV Si-min +5 more
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Development, characterization in vitro and in silico of coenzyme Q10 loaded myristic acid with different liquid lipids nanostructured lipid carriers [PDF]
Context: Nanostructured lipid carriers can enhance skin penetration of active substances. Coenzyme Q10 is a lipophilic antioxidant, that has poor skin penetration. This limitation is overcome by nanostructured lipid carriers.
Ni Luh Dewi Aryani +4 more
doaj
Impact of ciprofloxacin and coenzyme Q10 on spermatogenesis in mice
Background: Ciprofloxacin is commonly used to treat many bacterial infections. There are controversial reports regarding abnormalities in sperm parameters in laboratory animal and human studies after ciprofloxacin administration.
Reshna Kamal Albarzanji +2 more
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Background: Coenzyme Q10 is formulated into Nanostructured Lipid Carrier (NLC) added with peppermint oil (PO) 0% (F1), 1% (F2), 1.5% (F3) and 2% (F4) to increase its penetration.
Tristiana Erawati +5 more
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Mutagenicity of organically synthesized coenzyme Q10 (CoQ10) was determined by Ames assay in the presence and absence of S9 mix. The tester strains were Salmonella typhimurium TA98, TA100, TA1535, and TA1537, and Escherichia coli WP2 uvr A. CoQ10 displayed no mutagenicity in any tester strain at any dose tested. Therefore, organically synthesized CoQ10
IKEDA, Kazutaka +2 more
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The effect of coenzyme Q10 on dexamethasone-induced oxidative stress in rats testes
Background: Oxidative stress is a contributing factor in 30%–80% of infertile men. Objective: The aim of this study was to investigate the impact of coenzyme Q10 on dexamethasone-induced oxidative stress in rats testes.
Ahmed T Alahmar +4 more
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Neuronal cells depend on mitochondrial oxidative phosphorylation for most of their energy needs and therefore are at a particular risk for oxidative stress.
M. Somayajulu +5 more
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The study aims to examine the effects of coenzyme Q10, (a bioenergetic antioxidant), on the indexes of left ventricular remodeling, oxidative damage, and angiotensin-converting enzyme (ACE) level after acute myocardial infarction (AMI) with left ...
Ram B. Singh +3 more
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