Results 1 to 10 of about 43,892 (252)

Investigating the influence of ubiquinone blood level on the abilities of children with specific learning disorder

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2018
Background Ubiquinone has antioxidant properties and has been linked to cognitive performance in some neuropsychiatric disorders. Its role in specific learning disorder manifestations has not been previously investigated. Therefore, the aim of this study
Ehab Ragaa Abdelraouf   +6 more
doaj   +2 more sources

The risks of ubiquinone and β-carotene deficiency and metabolic disorders in patients with oral cancer

open access: yesBMC Cancer, 2020
Background Cancer development is mediated by oxidative stress and inflammation, which may correlate with metabolic disorders. The aim of this study was to evaluate antioxidant vitamins status and metabolic parameters in patients with oral cancer ...
Man-Yee Chan   +6 more
doaj   +1 more source

The Heptaprenyl Diphosphate Synthase (Coq1) Is the Target of a Lipophilic Bisphosphonate That Protects Mice against Toxoplasma gondii Infection

open access: yesmBio, 2022
Prenyldiphosphate synthases catalyze the reaction of allylic diphosphates with one or more isopentenyl diphosphate molecules to form compounds such as farnesyl diphosphate, used in, e.g., sterol biosynthesis and protein prenylation, as well as longer ...
Melissa A. Sleda   +9 more
doaj   +1 more source

Plasma coenzyme Q10 levels in type 2 diabetic patients with retinopathy [PDF]

open access: yesInternational Journal of Ophthalmology, 2013
AIM: To determine the relationship between proliferative diabetic retinopathy (PDRP) and plasma coenzyme Q10(CoQ10) concentration.METHODS: Patients with type 2 diabetes and PDRP were determined to be the case group (n=50).
Orhan Ates   +9 more
doaj   +1 more source

Proline Dehydrogenase and Pyrroline 5 Carboxylate Dehydrogenase from Mycobacterium tuberculosis: Evidence for Substrate Channeling

open access: yesPathogens, 2023
In Mycobacterium tuberculosis, proline dehydrogenase (PruB) and ∆1-pyrroline-5-carboxylate (P5C) dehydrogenase (PruA) are monofunctional enzymes that catalyze proline oxidation to glutamate via the intermediates P5C and L-glutamate-γ-semialdehyde.
Santosh Kumar   +6 more
doaj   +1 more source

Evaluation of Coenzyme Q10 Redox Status as a Biomarker of Oxidative Stress

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2019
The article examines the role of ubiquinone as a redox molecule whose functions consist in electron transport in the mitochondrial respiratory chain and regeneration of endogenous antioxidants.
O. A. Goroshko   +3 more
doaj   +1 more source

The Use of Coenzyme Q10 in Cardiovascular Diseases

open access: yesAntioxidants, 2021
CoQ10 is an endogenous antioxidant produced in all cells that plays an essential role in energy metabolism and antioxidant protection. CoQ10 distribution is not uniform among different organs, and the highest concentration is observed in the heart ...
Yoana Rabanal-Ruiz   +2 more
doaj   +1 more source

Effect of p-chlorophenoxyisobutyrate (CPIB) fed to rats on hepatic biosynthesis and catabolism of ubiquinone

open access: yesJournal of Lipid Research, 1968
The effect of p-chlorophenoxyisobutyrate (CPIB) feeding on cholesterol and ubiquinone metabolism in rats was investigated. The results obtained from acetate-l-14C and mevalonate-2-14C incorporation studies both in vivo and in vitro confirm the results of
M.R. Lakshmanan   +2 more
doaj   +1 more source

Acid-Sensing Histidine Kinase With a Redox Switch

open access: yesFrontiers in Microbiology, 2021
The EvgS/EvgA two-component signal transduction system in Escherichia coli is activated under mildly acidic pH conditions. Upon activation, this system induces the expression of a number of genes that confer acid resistance.
Shinya Inada   +3 more
doaj   +1 more source

Coenzyme Q at the Hinge of Health and Metabolic Diseases

open access: yesAntioxidants, 2021
Coenzyme Q is a unique lipidic molecule highly conserved in evolution and essential to maintaining aerobic metabolism. It is endogenously synthesized in all cells by a very complex pathway involving a group of nuclear genes that share high homology among
Juan Diego Hernández-Camacho   +4 more
doaj   +1 more source

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