Results 31 to 40 of about 36,766 (230)

In vitro Ubiquinone Supplementation Increased Postthaw Sperm Motility in Severe Oligozoospermia

open access: yesBiomolecular and Health Science Journal
Introduction: Severe oligozoospermia (
Fachry Achmad Prodjokusumo   +4 more
doaj   +1 more source

Specific and rapid analysis of ubiquinones using Craven's reaction and HPLC with postcolumn derivatization

open access: yesJournal of Lipid Research, 2007
A new method for the analysis of ubiquinones in various samples was developed using an HPLC system with postcolumn derivatization. Craven's reaction, a specific color reaction for the analysis of ubiquinones, was used in the system.
Haruo Shimada   +2 more
doaj   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

open access: yesAdvanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

The Impact of Natural Calcium Carbonate and Ubiquinone on Bone Mineral Density in Rabbits

open access: yesJournal of Applied Veterinary Sciences, 2021
This study investigates the effect of Ubiquinone and/or calcium carbonate (CaCO3) on bone mineral density (BMD) in rabbits at the healing site in mandibular bone postoperatively.
Ahmed A. Hussein, Ghada A. Taqa
doaj   +1 more source

Identification of the Ubiquinone-binding Domain in QPs1 of Succinate-Ubiquinone Reductase [PDF]

open access: yesJournal of Biological Chemistry, 1995
An azidoubiquinone derivative, 3-azido-2-methyl-5-methoxy [3H]-6-decyl-1,4-benzoquinone ([3H]azido-Q), was used to study the ubiquinone-protein interaction and to identify ubiquinone-binding proteins in bovine heart mitochondrial succinate-ubiquinone reductase.
G Y, Lee, D Y, He, L, Yu, C A, Yu
openaire   +2 more sources

DHODH Drives Sunitinib Resistance Via a Non‐Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC

open access: yesAdvanced Science, EarlyView.
This non‑enzymatic function of DHODH drives sunitinib resistance by competing with TRIM37 to block TRIM28 ubiquitination, thereby stabilizing TRIM28 and activating VEGFA transcription. Disrupting the DHODH–TRIM28 interaction with lisaftoclax restores drug sensitivity.
Shijie Qian   +10 more
wiley   +1 more source

Ubiquinone biosynthesis in microorganisms [PDF]

open access: yesFEMS Microbiology Letters, 2001
The quinoid nucleus of the benzoquinone, ubiquinone (coenzyme Q; Q), is derived from the shikimate pathway in bacteria and eukaryotic microorganisms. Ubiquinone is not considered a vitamin since mammals synthesize it from the essential amino acid tyrosine.
openaire   +2 more sources

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

open access: yesAdvanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang   +19 more
wiley   +1 more source

The ubiquinone content of animal tissues. A survey of the occurrence of ubiquinone in vertebrates [PDF]

open access: yesBiochemical Journal, 1967
1. A method was developed for the analysis of ubiquinone in animal tissues and the recovery of added ubiquinone tested in liver of the rat, Crocodylus porosus and Squalus acanthias. 2. The ubiquinone content of heart, liver and gut (or breast muscle in birds) was measured in 67 different animal species, selected to be representative of all the ...
A T, Diplock, G A, Haslewood
openaire   +2 more sources

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang   +13 more
wiley   +1 more source

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