Results 1 to 10 of about 13,810 (181)

Ubiquinone supplementation during lovastatin treatment: effect on LDL oxidation ex vivo1

Journal of Lipid Research, 1998
A randomized, double-masked, placebo-controlled cross-over trial was carried out to evaluate whether ubiquinone supplementation (180 mg daily) corrects impaired defence against initiation of oxidation of low density lipoprotein (LDL) related to effective
Ari Palomäki, Kimmo Malminiemi, Tiina Solakivi, Outi Malminiemi   +3 more
doaj   +1 more source

The Effects of Ubiquinol Intake and Sociophysical Training on the Activation of Psychological and Infrared Camera-Measured Body Temperature Physiology and Blood Molecular Markers: A Pilot Study among Healthy Female Older Adults

Applied Sciences
A combination of existing treatments with sensing technology may be the most appropriate approach for incurable neuropsychiatric disorders. Dietary antioxidant supplementation, exercise, and cognitive training are individually well-established treatments
Makoto Ota, Masanori Hariyama, Ricki Colman, Mamiko Koshiba   +3 more
doaj   +1 more source

Study protocol, randomized controlled trial: reducing symptom burden in patients with heart failure with preserved ejection fraction using ubiquinol and/or D-ribose

BMC Cardiovascular Disorders, 2018
Background Heart failure (HF), the leading cause of morbidity and mortality in the US, affects 6.6 million adults with an estimated additional 3 million people by 2030.
Janet D. Pierce, Diane E. Mahoney, John B. Hiebert, Amanda R. Thimmesch, Francisco J. Diaz, Carol Smith, Qiuhua Shen, Dinesh Pal Mudaranthakam, Richard L. Clancy   +8 more
doaj   +1 more source

Fluorescence Studies of the Interactions of Ubiquinol‐10 with Liposomes

Photochemistry and Photobiology, 2007
AbstractUbiquinone‐10 plays a central role in energy production and its reduced form, ubiquinol‐10 is also capable of acting as a potent radical scavenging antioxidant against membrane lipid peroxidation. Efficiency of this protection depends mostly on its localization in lipid bilayer.
Fiorini, Rosamaria, Ragni, Letizia, Ambrosi, Simona, Littarru, Gian Paolo, Gratton, Enrico, Hazlett, Theodore   +5 more
openaire   +4 more sources

CoQ10 and Cognition a Review and Study Protocol for a 90-Day Randomized Controlled Trial Investigating the Cognitive Effects of Ubiquinol in the Healthy Elderly

Frontiers in Aging Neuroscience, 2019
Introduction: With an aging population there is an important need for the development of effective treatments for the amelioration of cognitive decline.
Con Stough, Madeleine Nankivell, David A. Camfield, Naomi L. Perry, Andrew Pipingas, Helen Macpherson, Keith Wesnes, Keith Wesnes, Keith Wesnes, Ruchong Ou, David Hare, Judy de Haan, Geoffrey Head, Peter Lansjoen, Alena Langsjoen, Brendan Tan, Matthew P. Pase, Matthew P. Pase, Matthew P. Pase, Rebecca King, Renee Rowsell, Oliver Zwalf, Yossi Rathner, Matthew Cooke, Franklin Rosenfeldt, Franklin Rosenfeldt   +25 more
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The Mitochondrial Interplay of Ubiquinol and Nitric Oxide in Endotoxemia

, 2004
Publisher Summary This chapter focuses on role of ubiquinol (UQ) and nitric oxide in endotoxemia. UQ is endogenously synthesized in every organ in a specific pathway branched from cholesterol biosynthesis. Organs have different ubiquinol content depending on the activity of the biosynthetic pathway.
Lisdero, Constanza L., Carreras, Maria Cecilia, Meulemans, Alain, Melani, Mariana, Aubier, Michel, Boczkowski, Jorge, Poderoso, Juan José   +6 more
openaire   +3 more sources

An AlphaFold Structure Analysis of COQ2 as Key a Component of the Coenzyme Q Synthesis Complex

Antioxidants
Coenzyme Q (CoQ) is a lipidic compound that is widely distributed in nature, with crucial functions in metabolism, protection against oxidative damage and ferroptosis and other processes.
María de los Ángeles Vargas-Pérez, Damien Paul Devos, Guillermo López-Lluch   +2 more
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COMPARATIVE IN VITRO RELEASE STUDY OF UBIQUINONE, UBIQUINOL ACETATE, AND DELT UBIQUINOL ACETATE

Ubiquinone is the oxidized form of Coenzyme Q10 (CoQ10) and has been the industry standard for supplementation for decades. In the body’s energy production cycle, Ubiquinone’s primary role is to accept electrons.[1] However, it faces a significant biological hurdle: it is a large, fat-soluble molecule that is notoriously difficult for the ...
openaire   +3 more sources

Correlations between Oxidative DNA Damage, Oxidative Stress and Coenzyme Q10 in Patients with Coronary Artery Disease

International Journal of Medical Sciences, 2012
The correlation of coronary artery disease (CAD) with pro-oxidant/antioxidant balance and oxidative DNA damage was investigated.Seventy-seven patients with CAD and 44 healthy individuals as control were included in this study.
Yüksel KAYA, Ayşegül ÇEBİ, Nihat SÖYLEMEZ, Halit DEMİR, Hamit Hakan ALP, Ebubekir BAKAN
doaj  

THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW)

Разработка и регистрация лекарственных средств, 2019
In the human body, coenzyme Q10 is in the oxidized and reduced forms and can be found in every organ. The review describes modern HPLC methods of coenzyme Q10 analysis using electrochemical, spectrophotometric and mass spectrometric detectors.
V. I. Zozina, O. A. Goroshko, L. M. Krasnykh, V. G. Kukes   +3 more
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