Results 31 to 40 of about 16,390 (163)

Bioavailability of Coenzyme Q₁₀: An Overview of the Absorption Process and Subsequent Metabolism

Antioxidants, 2020
A lack of understanding of the processes determining the absorption and subsequent metabolism of coenzyme Q10 (CoQ10) has resulted in some manufacturers’ making incorrect claims regarding the bioavailability of their CoQ10 supplements, with potential ...
David Mantle, Alex Dybring
doaj   +1 more source

The Protective Effect of Ubiquinone against the Amyloid Peptide in Endothelial Cells Is Isoprenoid Chain Length-Dependent

Antioxidants, 2021
Vascular brain pathology constitutes a common feature in neurodegenerative diseases that could underlie their development. Indeed, vascular dysfunction acts synergistically with neurodegenerative changes to exacerbate the cognitive impairment found in ...
Javier Frontiñán-Rubio, Yoana Rabanal-Ruiz, Mario Durán-Prado, Francisco Javier Alcain   +3 more
doaj   +1 more source

Activity of respiratory chain cytochrome complexes and cytochromes content in the rat kidney mitochondria under different nutrients content in a diet [PDF]

The Ukrainian Biochemical Journal, 2023
An important role in ensuring the functioning of the respiratory chain belongs to the cytochrome part, which includes complexes III (ubiquinol-cytochrome c oxidoreductase) and IV (cytochrome c oxidase). The key components of these enzymatic complexes are
H. P. Kopylchuk, O. M. Voloshchuk
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Intravenous Administration of Coenzyme Q10 in Acute Period of Cerebral Ischemia Decreases Mortality by Reducing Brain Necrosis and Limiting Its Increase within 4 Days in Rat Stroke Model

Antioxidants, 2020
Oxidative stress plays a key role in the pathogenesis of ischemic stroke. Coenzyme Q10 has a multi-targeting effect and may protect the brain against ischemic damage.
Olga N. Obolenskaia, Evgeniya A. Gorodetskaya, Elena I. Kalenikova, Margarita A. Belousova, Mikhail V. Gulyaev, Valery G. Makarov, Yury A. Pirogov, Oleg S. Medvedev   +7 more
doaj   +1 more source

Novel Cationic Prodrug of Ubiquinol-10 Enhances Intestinal Absorption via Efficient Formation of Nanosized Mixed-Micelles with Bile Acid Anions

Molecules, 2020
The aim of this study was to develop a prodrug of ubiquinol-10 (UqH-10), the active form of ubiquinone-10 (Uq-10), for oral delivery. Bioavailability of UqH-10 is hampered by its high susceptibility to oxidation and water-insolubility.
Shuichi Setoguchi, Ryoji Hidaka, Nami Nagata-Akaho, Daisuke Watase, Mitsuhisa Koga, Kazuhisa Matsunaga, Yoshiharu Karube, Jiro Takata   +7 more
doaj   +1 more source

The Use of the Coenzyme Q₁₀ as a Food Supplement in the Management of Fibromyalgia: A Critical Review

Antioxidants, 2022
The coenzyme Q10 is a naturally occurring benzoquinone derivative widely prescribed as a food supplement for different physical conditions and pathologies.
Luca Campisi, Concettina La Motta
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Long-term stability of ubiquinol-10 in natural miso without artificial antioxidants [PDF]

PDFUbiquinol-10, the reduced form of coenzyme Q10, has higher bioavailability but lower stability than ubiquinone-10, the oxidized form of coenzyme Q10.
Toshikazu, SUZUKI, Takao, YAMAGUCHI, Kazunori, HOSOE   +2 more
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Effect of ubiquinol on cardiorespiratory fitness during high-altitude acclimatization and de-acclimatization in healthy adults: the Shigatse CARdiorespiratory fitness study design

Frontiers in Cardiovascular Medicine, 2023
Cardiorespiratory function influences exercise capacity and is an important determinant of high-altitude adaptation. Some studies have investigated the characteristics of changes in cardiorespiratory fitness during high-altitude acclimatization. However,
Jie Yang, Jie Yang, Xiaowei Ye, Xiaowei Ye, Zhen Liu, Zhen Liu, Mengjia Sun, Mengjia Sun, Shiyong Yu, Shiyong Yu, Hailin Lv, Hailin Lv, Boji Wu, Boji Wu, Chen Zhang, Chen Zhang, Wenzhu Gu, Wenzhu Gu, Jingyu He, Jingyu He, Xuhong Wang, Xuhong Wang, Lan Huang, Lan Huang   +23 more
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Effects of lifetime supplementation with ubiquinol 10 on the lifespan and progression of aging in female C57BL/6 mice

Experimental Gerontology
Supplementation with ubiquinol 10 has been shown to improve the health of experimental animals and elderly individuals. The present study investigated the effects of lifetime supplementation with ubiquinol 10 on the progression of aging and lifespan in ...
Yuichi Igarashi, Sakiko Hamada, Jin Dai, Masayuki Mori, Hiroki Miyahara, Jinko Sawashita, Keiichi Higuchi   +6 more
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Ubiquinol Improves Symptoms in Children with Autism [PDF]

, 2014
Background. Autism is a spectrum of neurodevelopmental disorders with manifestation within 3 years after birth. Manifestations of autism include behavior problems (hyperactivity, toys destruction, self-harm, and agression) and sleep and eating disorders.
Nakladal, Dalibor, Kucharska, Jarmila, Ostatnikova, Daniela, Gvozdjakova, Anna, Babinska, Katarina, Crane, Fred L.   +5 more
core   +1 more source