Results 51 to 60 of about 16,390 (163)

Fluorescence studies of the interactions of ubiquinol-10 with liposomes. [PDF]

, 2008
Photochem Photobiol. 2008 Jan-Feb;84(1):209-14. Fluorescence studies of the interactions of ubiquinol-10 with liposomes. Fiorini R, Ragni L, Ambrosi S, Littarru GP, Gratton E, Hazlett T.
Enrico Gratton, Letizia Ragni, AMBROSI, Simona, HAZLETT T., Rosamaria Fiorini, Hazlett, Theodore, Simona Ambrosi, Gian Paolo Littarru, Gratton, Enrico, GRATTON E, FIORINI, ROSAMARIA, LITTARRU, GIAN PAOLO, RAGNI, Letizia, Theodore Hazlett   +13 more
core   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi, Shogo Yoshimoto, Katsutoshi Hori   +2 more
wiley   +1 more source

Features of the influence of the antioxidant ethylmethylhydroxypyridine malate and the drug ubidecarenone on plasma concentrations of ubiquinone, ubiquinol and the redox state of coenzyme Q10

Фармакокинетика и Фармакодинамика
Relevance. Coenzyme Q10 is one of the main components that maintain the balance of the body's redox regulatory system. Although some studies have examined plasma concentrations of CoQ10 in various diseases, the distribution of ubiquinol and ubiquinone ...
V. I. Zozina, S. N. Kondratenko, E. V. Shikh, L. M. Krasnykh, E. S. Melnikov, V. G. Kukes   +5 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

On the specificity of activation of mitochondrial succinate dehydrogenase by ubiquinol

, 1972
Activation of succinate dehydrogenase on preincubation with mitochondria is not specific for ubiquinol-10. Other homologues of ubiquinol, plastoquinol, o-, m- and p-quinols, 2-nitro-, 4-nitro- and 2,4-dinitro- phenols showed different degrees of ...
Susheela, L, Ramasarma, T
core   +1 more source

Oxidative stress and mitochondrial function : role of ubiquinol as antioxidant

, 1996
Over the last three decades it has been established that biquinone (coenzyme Q), in addition to its function as an electron and proton carrier in the respiratory chain, acts in its reduced form (ubiquinol) as an antioxidant. The main theme of this thesis
Patrik Andrée (19528216)
core   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

PROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima, Wilson Dias Segura, Leonardo Brogliato de Moraes, Reinaldo Souza Oliveira, Pedro Henrique Corteletti Manfio, Alison Felipe Alencar Chaves, Wagner Luiz Batista   +6 more
wiley   +1 more source

Effects of ubiquinol on metabolic profile in prediabetic patients: A randomized, double-blinded, placebo-controlled pilot study

Clinical Nutrition Open Science
Background/objectives: Prediabetes not only increase the risk of developing diabetes, but it is also associated with the development of cardiovascular disease, chronic kidney disease, neuropathy, and retinopathy.
Pasita Palakornkitti, Romun Leaovitavat, Paphitchaya Thetsana, Patana Teng-umnuay   +3 more
doaj   +1 more source

Time‐Resolved Effects of Cold Atmospheric Plasma on E. coli GW‐AmxH19 Transcriptome and Proteome in an Emulated Wastewater Environment

PROTEOMICS, EarlyView.
ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt, Dominik Schneider, Julia Rielicke, Susanne Sievers, Veronika Hahn, Mechthild Bömeke, Anja Poehlein, Dirk Albrecht, Juergen F. Kolb, Katharina Riedel, Rolf Daniel, Daniela Zühlke   +11 more
wiley   +1 more source