Results 61 to 70 of about 16,390 (163)

Effects of Feeding Coenzyme Q10-Ubiquinol on Plasma Coenzyme Q10 Concentrations and Semen Quality in Stallions [PDF]

Although coenzyme Q10 (CoQ10) serves as an antioxidant and energy source for spermatozoa when added to stallion semen prior to cooling or freezing, the effects of feeding CoQ10 on semen quality have not been studied. We assessed the effects of daily oral
Leadon, DP, Bayly, WM, Hargreaves, IP, Ruiz, AJ, Tibary, A, Heaton, R   +5 more
core   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca, Violeta Larios‐Serrato, María Luisa Labra‐Barrios, Emmanuel Ríos‐Castro, Carlos Alberto Castañón‐Sánchez, Rodolfo Moreno‐Castillo, Erika Beatriz Ángeles‐Morales, Juan Pedro Luna‐Arias   +7 more
wiley   +1 more source

Ubiquinol affects the expression of genes involved in PPARα signalling and lipid metabolism without changes in methylation of CpG promoter islands in the liver of mice

, 2011
Coenzyme Q10 is an essential cofactor in the respiratory chain and serves as a potent antioxidant in biological membranes. Recent studies in vitro and in vivo provide evidence that Coenzyme Q10 is involved in inflammatory processes and lipid metabolism ...
Schmelzer, Constance, Kitano, Mitsuaki, Constance Schmelzer, Mitsuaki Kitano, Frank Döring, Kazunori Hosoe, Döring, Frank, Hosoe, Kazunori   +7 more
core   +1 more source

Mitochondrial alterations as potential early events in neuromuscular junction remodelling with muscle disuse

Experimental Physiology, EarlyView.
Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova, Evgenii Lysenko, Fabio Sarto, Mladen Gasparini, Boštjan Šimunic, Rado Pišot, Marco V. Narici   +6 more
wiley   +1 more source

Rates of oxidation of 150 µM ubiquinol-1 by these membrane fractions.

, 2013
Rates of oxidation of 150 µM ubiquinol-1 by these membrane fractions.
Patrick J. Keeling (82468), Catherine Elliot (367198), Lena Burri (320078), Yasutoshi Kido (367200), Bryony A. P. Williams (367195), Kiyoshi Kita (22197), Anthony L. Moore (367203)   +6 more
core   +1 more source

Omental adipocyte hypertrophy relates to coenzyme Q10 redox state and lipid peroxidation in obese women

Journal of Lipid Research, 2015
Occurrence of oxidative stress in white adipose tissues contributes to its dysfunction and the development of obesity-related metabolic complications. Coenzyme Q10 (CoQ10) is the single lipophilic antioxidant synthesized in humans and is essential for ...
Thomas Grenier-Larouche, Anne Galinier, Louis Casteilla, André C. Carpentier, André Tchernof   +4 more
doaj   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, Volume 13, Issue 61, 3 November 2026.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

The Role of Mitochondrial Homeostasis in the Pathogenesis of Chronic Rhinosinusitis

Immunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
The vicious cycle between pathogenic factors‐induced inflammation, oxidative stress, and mitochondrial dysfunction in the context of chronic rhinosinusitis. Created in BioRender. Taghizadeh‐Hesary (2026) https://BioRender.com/k5f4t1f. ABSTRACT Background Chronic rhinosinusitis (CRS) is a common clinical condition characterized by persistent ...
Babak Ghalehbaghi, Morteza Fallahpour, Mohammad Nabavi, Maryam Jalessi, Hadi Ghanbari, Nasibeh Khayer, Farzad Taghizadeh‐Hesary   +6 more
wiley   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, Volume 111, Issue 11, Page 5236-5249, 1 November 2026.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Ubiquinol-binding site in the alternative oxidase: mutagenesis reveals features important for substrate binding and inhibition

, 2010
The alternative oxidase (AOX) is a non-protonmotive ubiquinol oxidase that is found in all plants, some fungi, green algae, bacteria and pathogenic protozoa.
Anthony Moore (4460455), Catherine Elliott (3159567), Mary Albury (4460599)   +2 more
core