Results 61 to 70 of about 25,325 (230)

RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells [PDF]

, 2019
Cardiac mesenchymal stem cells (C-MSC) play a key role in maintaining normal cardiac function under physiological and pathological conditions. Glycolysis and mitochondrial oxidative phosphorylation predominately account for energy production in C-MSC ...
Jin, Yue, Kim, Il-man, Shen, Yan, Su, Xuan, Tang, Yaoliang, Weintraub, Neal L.   +5 more
core   +1 more source

Features of the influence of the antioxidant ethylmethylhydroxypyridine malate and the drug ubidecarenone on plasma concentrations of ubiquinone, ubiquinol and the redox state of coenzyme Q10

Фармакокинетика и Фармакодинамика
Relevance. Coenzyme Q10 is one of the main components that maintain the balance of the body's redox regulatory system. Although some studies have examined plasma concentrations of CoQ10 in various diseases, the distribution of ubiquinol and ubiquinone ...
V. I. Zozina, S. N. Kondratenko, E. V. Shikh, L. M. Krasnykh, E. S. Melnikov, V. G. Kukes   +5 more
doaj   +1 more source

Effects of diamagnetic levitation on bacterial growth in liquid [PDF]

, 2010
Diamagnetic levitation is a technique that uses a strong, spatially-varying magnetic field to levitate diamagnetic materials, such as water and biological cells. This technique has the potential to simulate aspects of weightlessness, on the Earth.
Camelia E. Dijkstra, Catherine E. D. Rees, Laurence Eaves, Michael R. Davey, Oliver J. Larkin, Paul Anthony, Richard J. A. Hill   +6 more
core   +1 more source

Transcription, signaling receptor activity, oxidative phosphorylation, and fatty acid metabolism mediate the presence of closely related species in distinct intertidal and cold-seep habitats [PDF]

, 2015
Bathyal cold seeps are isolated extreme deep-sea environments characterized by low species diversity while biomass can be high. The Hakon Mosby mud volcano (Barents Sea, 1,280 m) is a rather stable chemosynthetic driven habitat characterized by prominent
Derycke, Sofie, Van Belleghem, Steven, Van Campenhout, Jelle, Vanreusel, Ann   +3 more
core   +2 more sources

Effects of ubiquinol on metabolic profile in prediabetic patients: A randomized, double-blinded, placebo-controlled pilot study

Clinical Nutrition Open Science
Background/objectives: Prediabetes not only increase the risk of developing diabetes, but it is also associated with the development of cardiovascular disease, chronic kidney disease, neuropathy, and retinopathy.
Pasita Palakornkitti, Romun Leaovitavat, Paphitchaya Thetsana, Patana Teng-umnuay   +3 more
doaj   +1 more source

Metabolomic and lipidomic signatures of Helicobacter pylori infection: Unveiling biochemical pathways associated with neurodegeneration

iMetaOmics, EarlyView.
Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal, Tarun Prakash Verma, Siddharth Singh, Hamendra Parmar, Hem Chandra Jha   +4 more
wiley   +1 more source

Superior Anti-arrhythmogenic Effect of Combined Conditioning with Nicotinamide Mononucleotide and Ubiquinol in Myocardial Ischemia/Reperfusion Injury in Aged Rats [PDF]

Advanced Pharmaceutical Bulletin
Purpose: Lethal ventricular arrhythmias are a significant clinical concern following reperfusion therapies in elderly patients with myocardial infarction.
Behnaz Mokhtari, Amirhossein Jessri, Samad Ghaffari, Reza Badalzadeh   +3 more
doaj   +1 more source

Branched‐Chain Amino and Keto Acids Reduce Hepatocyte Lipid Droplet Size and Number via Distinct Proteomic Pathways

PROTEOMICS, EarlyView.
ABSTRACT Branched‐chain amino acids (BCAA) and their corresponding keto acids (BCKA) have been associated with changes in hepatic lipid metabolism and the resulting alterations in intracellular triglyceride concentrations. In this study, we utilized a previously established hepatocyte model to investigate the impact of BCAA and BCKA supplementation on ...
Jayasimha R. Daddam, Mounica Sura, Edward Kolodziej, Maria Gojcaj, Zheng Zhou   +4 more
wiley   +1 more source

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. [PDF]

, 2019
Ferroptosis is a form of regulated cell death that is caused by the iron-dependent peroxidation of lipids1,2. The glutathione-dependent lipid hydroperoxidase glutathione peroxidase 4 (GPX4) prevents ferroptosis by converting lipid hydroperoxides into non-
A Arroyo, Bingqi Tong, BR Stockwell, Breanna Ford, Daniel K. Nomura, DL Tribble, DW Morgens, I Ingold, James A. Olzmann, JL Macdonald, Joseph M. Hendricks, K Bersuker, K Shimada, Kirill Bersuker, KR Marshall, L Magtanong, Leslie Magtanong, M Hayano, M Wu, Melissa A. Roberts, MG Rees, Michael C. Bassik, MJ Hangauer, Peter H. Tang, PH Tang, R Stocker, Roberto Zoncu, Scott J. Dixon, SJ Dixon, SJ Dixon, SJ Dixon, T Inoue, T Inoue, T Takahashi, TB Nguyen, Thomas J. Maimone, VS Viswanathan, WS Yang, WS Yang, X Sun, Y Ohiro, Y Zhang, Y Zou, Zhipeng Li   +43 more
core   +1 more source

Research progress in ferroptosis regulation in the treatment of liver diseases

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Ferroptosis is a form of cell death that results from accumulation of lipid reactive oxygen species, marked by iron-dependent oxidative damage of phospholipids. Accumulation of iron and lipid hydroperoxides are hallmarks of ferroptosis.
CHEN Chen, CHENG Zhuoan, WANG Cun, XIA Qiang   +3 more
doaj   +1 more source