Results 51 to 60 of about 7,056 (155)

Supercritical Fluid Extraction and Ultra Performance Liquid Chromatography of Respiratory Quinones for Microbial Community Analysis in Environmental and Biological Samples

Molecules, 2012
Microbial community structure plays a significant role in environmental assessment and animal health management. The development of a superior analytical strategy for the characterization of microbial community structure is an ongoing challenge.
Koichi Fujie, Hiroyuki Daimon, Yoichi Atsuta, Muhammad Hanif   +3 more
doaj   +1 more source

Design of Nanostructured Lipid Carriers Ubiquinone-10 for Transdermal Treatment [PDF]

, 2018
Ubiquinone-10 is a cellular endogenous antioxidant that resides in the epidermal layer. Ubiquinone-10 can increase the production of basal membrane components, fibroblast proliferation and protect cells from oxidative damage, so with increasing age, the ...
M Fatchur Rochman, Esti Hendradi, Isnaeni   +2 more
core   +2 more sources

Is High-Dose Ubiquinone Therapy Before Cardiac Surgery Enough to Reduce the Incidence of Cardiac Surgery-Associated Acute Kidney Injury? A Randomized Controlled Trial

Antioxidants
Cardiac surgery-related acute kidney injury (CS-AKI) is a decrease in kidney function after open-heart surgery, affecting up to 50% of patients. The pathophysiology of CS-AKI involves ischemia–reperfusion injury, inflammation, and oxidative stress ...
Hrvoje Vučemilović, Ruben Kovač, Lada Stanišić, Ana Sanader Vučemilović, Dina Mrčela, Benjamin Benzon, Mladen Carev   +6 more
doaj   +1 more source

Coenzyme Q₁₀: Clinical Applications in Cardiovascular Diseases

Antioxidants, 2020
Coenzyme Q10 (CoQ10) is a ubiquitous factor present in cell membranes and mitochondria, both in its reduced (ubiquinol) and oxidized (ubiquinone) forms.
Alma Martelli, Lara Testai, Alessandro Colletti, Arrigo F. G. Cicero   +3 more
doaj   +1 more source

Bioavailability of Coenzyme Q₁₀: An Overview of the Absorption Process and Subsequent Metabolism

Antioxidants, 2020
A lack of understanding of the processes determining the absorption and subsequent metabolism of coenzyme Q10 (CoQ10) has resulted in some manufacturers’ making incorrect claims regarding the bioavailability of their CoQ10 supplements, with potential ...
David Mantle, Alex Dybring
doaj   +1 more source

Ubiquinone and carotene production in the Mucorales Blakeslea and Phycomyces

, 2007
The filamentous fungi Phycomyces blakesleeanus and Blakeslea trispora (Zygomycota, Mucorales) are actual or potential industrial sources of beta-carotene and lycopene.
Cerda-Olmedo, E., Vera Kuzina, Kuzina, Vera, Enrique Cerdá-Olmedo   +3 more
core   +1 more source

Intravenous Administration of Coenzyme Q10 in Acute Period of Cerebral Ischemia Decreases Mortality by Reducing Brain Necrosis and Limiting Its Increase within 4 Days in Rat Stroke Model

Antioxidants, 2020
Oxidative stress plays a key role in the pathogenesis of ischemic stroke. Coenzyme Q10 has a multi-targeting effect and may protect the brain against ischemic damage.
Olga N. Obolenskaia, Evgeniya A. Gorodetskaya, Elena I. Kalenikova, Margarita A. Belousova, Mikhail V. Gulyaev, Valery G. Makarov, Yury A. Pirogov, Oleg S. Medvedev   +7 more
doaj   +1 more source

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction

Bioscience Reports, 2013
Some mutations of the DHODH (dihydro-orotate dehydrogenase) gene lead to postaxial acrofacial dysostosis or Miller syndrome. Only DHODH is localized at mitochondria among enzymes of the de novo pyrimidine biosynthesis pathway.
JingXian Fang, Takeshi Uchiumi, Mikako Yagi, Shinya Matsumoto, Rie Amamoto, Shinya Takazaki, Haruyoshi Yamaza, Kazuaki Nonaka, Dongchon Kang   +8 more
doaj   +1 more source

Novel Cationic Prodrug of Ubiquinol-10 Enhances Intestinal Absorption via Efficient Formation of Nanosized Mixed-Micelles with Bile Acid Anions

Molecules, 2020
The aim of this study was to develop a prodrug of ubiquinol-10 (UqH-10), the active form of ubiquinone-10 (Uq-10), for oral delivery. Bioavailability of UqH-10 is hampered by its high susceptibility to oxidation and water-insolubility.
Shuichi Setoguchi, Ryoji Hidaka, Nami Nagata-Akaho, Daisuke Watase, Mitsuhisa Koga, Kazuhisa Matsunaga, Yoshiharu Karube, Jiro Takata   +7 more
doaj   +1 more source

Characterization of the reaction of decoupling ubiquinone with bovine mitochondrial respiratory complex I

, 2016
We previously produced the unique ubiquinone QT (“decoupling” quinone), the catalytic reduction of which in NADH-quinone oxidoreduction with bovine heart mitochondrial NADH-ubiquinone oxidoreductase (complex I) is completely decoupled from proton ...
Hideto Miyoshi (697083), Takahiro Masuya (1704181), Kenji Okuda (334795), Masatoshi Murai (697079)   +3 more
core   +1 more source