Results 71 to 80 of about 7,056 (155)

Effect of dietary cholesterol and ubiquinone on isoprene synthesis in rat liver

, 1967
The effect of dietary cholesterol and ubiquinone on the synthesis of isoprene compounds in the liver, as tested by the incorporation of acetate-1-14C and mevalonate-2-14C, was studied in rats.
Ramasarma, T, Krishnaiah, KV, Joshi, VC
core   +1 more source

Identification of Ubiquinones in Honey: A New View on Their Potential Contribution to Honey’s Antioxidant State

Molecules, 2018
Honey is composed of macromolecules arranged into multicomponent colloidal particles dispersed in a supersaturated sugar solution. The core part of colloidal particles in honey is made up of high-molecular weight protein-polyphenol complexes. We designed
Katrina Brudzynski, Liset Maldonado-Alvarez   +1 more
doaj   +1 more source

IN VITRO STUDIES ON THE BIOSYNTHESIS OF UBIQUINONE

, 1960
Radioactive ubiquinone can be isolated from rat liver following intraperitoneal injections of C14-acetate or mevalonic acid. No detectable amount of radioactive ubiquinone could be isolated from liver homogenates, liver slices, or intestinal mucosa ...
W. E. J. Phillips
core   +1 more source

Ubiquinone binding, ubiquinone exclusion, and detailed cofactor conformation in a mutant bacterial reaction center

, 2000
The X-ray crystal structure of a Rhodobacter sphaeroides reaction center with the mutation Ala M260 to Trp (AM260W) has been determined. Diffraction data were collected that were 97.6% complete between 30.0 and 2.1 Angstrom resolution.
Cogdell, RJ, Isaacs, NW, McAuley, KE, Fyfe, PK, Ridge, JP, Jones, MR, Paul K. Fyfe, Justin P. Ridge, Neil W. Isaacs, Richard J. Cogdell, Katherine E. McAuley, Michael R. Jones   +11 more
core   +1 more source

Anti-Leukemic Activity of Ubiquinone-Based Compounds Targeting Trans-plasma Membrane Electron Transport

, 2016
Trans-plasma membrane electron transport (tPMET) is a ubiquinone-dependent cell survival pathway for maintaining intracellular redox homeostasis in rapidly dividing cells.
Carole Grasso (1965766), Michael V. Berridge (1965772), Robin A. J. Smith (1965769), Lesley Larsen (401144), Melanie McConnell (1965775)   +4 more
core   +1 more source

Inhibition of cholesterol biosynthesis in hypercholesterolemia: Is it the right choice? [PDF]

Journal of Medical Biochemistry, 2013
Cholesterol biosynthesis is a complex pathway comprising more than 20 biochemical reactions. Although the final product created in the pathway is cholesterol, the intermediate products, such as ubiquinone and dolichol, also provide vital metabolic ...
Coskun Abdurrahman, Serteser Mustafa
doaj  

Feedback-type inhibition of activity of 3-hydroxy-3-methylglutaryl coenzyme a reductase by ubiquinone

, 1992
Accompanying the decrease in serum cholesterol and increase in concentration of ubiquinone in liver and its microsomes, the activity, but not the protein, of HMG-CoA reductase decreased in ubiquinone-supplemented rats. A soluble 58-kDa preparation of HMG-
Ramasarma, T, Omkumar, RV, Gaikwad, Amos S   +2 more
core  

The electron transfer flavoprotein: Ubiquinone oxidoreductases

, 2010
Electron transfer flavoprotein:ubiqionone oxidoreductase (ETF-QO) is a component of the mitochondrial respiratory chain that together with electron transfer flavoprotein (ETF) forms a short pathway that transfers electrons from 11 different mitochondrial
Watmough, Nicholas J., Nicholas J. Watmough, Frerman, Frank E., Frank E. Frerman   +3 more
core   +1 more source

Impact of niacin combined with ubiquinone on inhibition of lipoprotein lipase as a mechanism of anti-obesity and antiatherogenic agents in rats fed on high-fat diet

Journal of Biological Research
Niacin is one of the B-complex vitamins that play an important role in metabolic pathways, while ubiquinone (Coenz-Q) is a component of the electron transport chain required for energy production.
Fatma A. Eissa, Taha A. Kumosani, Elie K. Barbour, Soonham S. Yaghmoor, Khalid M. El-Say, May M.M. Tadros, Said S. Moselhy   +6 more
doaj   +1 more source

Exploring the ubiquinone binding cavity of respiratory complex I

, 2007
Proton pumping respiratory complex I is a major player in mitochondrial energy conversion. Yet little is known about the molecular mechanism of this large membrane protein complex.
Brandt, Ulrich, Kerscher, Stefan, Tocilescu, Maja Aleksandra, Fendel, Uta, Zwicker, Klaus   +4 more
core   +1 more source