Results 81 to 90 of about 41,185 (159)

Impact of niacin combined with ubiquinone on inhibition of lipoprotein lipase as a mechanism of anti-obesity and antiatherogenic agents in rats fed on high-fat diet

open access: yesJournal of Biological Research
Niacin is one of the B-complex vitamins that play an important role in metabolic pathways, while ubiquinone (Coenz-Q) is a component of the electron transport chain required for energy production.
Fatma A. Eissa   +6 more
doaj   +1 more source

Inhibition of cholesterol biosynthesis in hypercholesterolemia: Is it the right choice? [PDF]

open access: yesJournal of Medical Biochemistry, 2013
Cholesterol biosynthesis is a complex pathway comprising more than 20 biochemical reactions. Although the final product created in the pathway is cholesterol, the intermediate products, such as ubiquinone and dolichol, also provide vital metabolic ...
Coskun Abdurrahman, Serteser Mustafa
doaj  

Exploring the ubiquinone binding cavity of respiratory complex I

open access: yes, 2007
Proton pumping respiratory complex I is a major player in mitochondrial energy conversion. Yet little is known about the molecular mechanism of this large membrane protein complex.
Brandt, Ulrich   +4 more
core   +1 more source

Impact of liposomal delivery on coenzyme Q10 absorption: a double-blind, placebo-controlled, randomized trial

open access: yesFrontiers in Nutrition
BackgroundCoenzyme Q10 (CoQ-10) plays a vital role in cellular energy production and protection against oxidative stress. However, its absorption from orally administered forms is limited due to its poor water solubility and relatively large molecular ...
Ralf Jäger   +6 more
doaj   +1 more source

IN VITRO STUDIES ON THE BIOSYNTHESIS OF UBIQUINONE

open access: yes, 1960
Radioactive ubiquinone can be isolated from rat liver following intraperitoneal injections of C14-acetate or mevalonic acid. No detectable amount of radioactive ubiquinone could be isolated from liver homogenates, liver slices, or intestinal mucosa ...
W. E. J. Phillips
core   +1 more source

Semiquinone oscillations as a tool for investigating the ubiquinone binding to photosynthetic reaction centers

open access: yes, 2015
Semiquinone oscillations induced by light pulses in the presence of exogenous electron donors are a valuable source of information on the kinetics and thermodynamics of ubiquinone chemistry relevant to the QB site of the photosynthetic reaction center ...
Agostiano, A.   +10 more
core   +1 more source

A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore.

open access: yes, 1998
We have investigated the regulation of the mitochondrial permeability transition pore (PTP) by ubiquinone analogues. We found that the Ca2+-dependent PTP opening was inhibited by ubiquinone 0 and decylubiquinone, whereas all other tested quinones ...
ICHAS F, BERNARDI, PAOLO, FONTAINE E
core  

Pantothenic acid deficiency and ubiquinone levels in rat liver mitochondria

open access: yes, 1959
A new group of naturally occurring homologous quinones referred to as ubiquinone or coenzyme Q (Q275) has been recognized in recent years. Structural studies have led to the characterization of these compounds as derivatives of 2, 3,-dimethoxy, 5-methyl ...
Aiyar, A. S.   +3 more
core   +1 more source

In vitro studies on the biosynthesis and reduction of ubiquinone

open access: yes, 2003
This thesis concerns the role of ubiquinone, the only endogenously synthesised lipid soluble antioxidant, in the cellular defence against peroxidation of proteins and lipids.The aims of the present investigations were to study the biosynthesis of ...
Tomas Nordman (19492789)
core  

Skin Penetration of Ubiquinone (Co-Q10) In Nanoemulsion Delivery System Using Virgin Cocunut Oil (Vco) [PDF]

open access: yes, 2018
Ubiquinone (co-Q10) is a topical anti-aging with low solubility in water, so its penetration into the skin is also low. To increase its penetration ubiquinone (co-Q10) was loaded in the nanoemulsion delivery system using virgin coconut oil (VCO) as oil ...
Noorma Rosita   +2 more
core  

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