Results 11 to 20 of about 43,892 (252)
Trends in Cell Biology, 2016 Ubiquinone (UQ; also known as coenzyme Q; CoQ) is a mobile component of the mitochondrial electron transport chain, where it acts as a pro-oxidant in its ubisemiquinone state. Despite this, UQ is also believed to be a membrane antioxidant. These properties place UQ at the center of hotly debated questions about how mitochondria and reactive oxygen ...
S Hekimi, Ying Wang
exaly +4 more sources
Synthesis of ubiquinone Q10 (Co Q10) from natural tobacco leaves
Results in ChemistryThe present research work is aimed to develop a methodology for the synthesis of Ubiquinone Q10 (CoQ10) from the natural tobacco leaves (Nicotiana tabacum L).
Venkata Manikya Kumar Ajjarapu
doaj +2 more sources
News in Ubiquinone Biosynthesis [PDF]
Chemistry & Biology, 2010 Ubiquinone (named because of its ubiquitous presence in organisms) functions as an electron carrier in the mitochondrial respiratory chain. Pierrel et al. (2010) have described the presence of new actors in the biosynthesis of this venerable molecule.
Rötig, Agnès
openaire +3 more sources
The NADH-ubiquinone reductase and succinate dehydrogenase activity in the rat kidney mitochondria under the conditions of different protein and sucrose content in the diet [PDF]
The Ukrainian Biochemical Journal, 2022 The NADH-ubiquinone reductase (EC 7.1.1.2) and succinate dehydrogenase (EC 1.3.5.1) activity, the levels of total ubiquinone and its redox forms, and the degree of oxidative modification of mitochondrial proteins in the rat kidney were investigated.
O. M. Voloshchuk +2 more
doaj +1 more source
Stability of Reduced and Oxidized Coenzyme Q10 in Finished Products
Antioxidants, 2021 The efficiency of coenzyme Q10 (CoQ10) supplements is closely associated with its content and stability in finished products. This study aimed to provide evidence-based information on the quality and stability of CoQ10 in dietary supplements and ...
Žane Temova Rakuša +2 more
doaj +1 more source
Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death. [PDF]
PLoS ONE, 2010 Prolonged opening of the mitochondrial permeability transition pore (PTP) leads to cell death. Various ubiquinone analogs have been shown to regulate PTP opening but the outcome of PTP regulation by ubiquinone analogs on cell fate has not been studied ...
Flavien Devun +5 more
doaj +1 more source
Antioxidants, 2020 The aim of this study is to investigate the glycemic profile, oxidative stress, and antioxidant capacity in athletes after 12 weeks of ubiquinone supplementation. It was a double-blinded, randomized, parallel, placebo-controlled study.
Chien-Chang Ho +6 more
doaj +1 more source
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2023 Oxidative stress and inflammation are connected to the development of metabolic disorders, such as diabetes. Diabetic-related oxidative stress is caused by the overproduction of oxidative-free radicals, which have been implicated in the mechanism of ...
Yousif Jameel Jbrael +1 more
doaj +1 more source
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
Relaxin-2: Shaping the Proteomic Landscape of Skeletal Muscle Physiology, Glucose Trafficking, and Mitochondrial Function in Rat. [PDF]
FASEB JCardioprotective hormone relaxin‐2 showed relevant effects on rat skeletal muscle by altering proteins linked to muscle function, regeneration, differentiation, mitochondrial function, glucose metabolism, and structural integrity and organization. Specifically, relaxin‐2 reduced the expression of 95 proteins, increased 32, and elicited unique proteins ...
Vázquez-Abuín X +11 more
europepmc +2 more sources