Results 21 to 30 of about 7,056 (155)

Acid-Sensing Histidine Kinase With a Redox Switch

open access: yesFrontiers in Microbiology, 2021
The EvgS/EvgA two-component signal transduction system in Escherichia coli is activated under mildly acidic pH conditions. Upon activation, this system induces the expression of a number of genes that confer acid resistance.
Shinya Inada   +3 more
doaj   +1 more source

Ubiquinone-Nanostructured Lipid Carriers Hydrogel Mask for Antiaging: the Journey so Far [PDF]

open access: yes, 2020
Aging of the skin become a common problem in the society, especially in women. Sun exposure is a very influential factor in the occurrence of skin aging.
Widji Soeratri   +2 more
core   +1 more source

Coenzyme Q at the Hinge of Health and Metabolic Diseases

open access: yesAntioxidants, 2021
Coenzyme Q is a unique lipidic molecule highly conserved in evolution and essential to maintaining aerobic metabolism. It is endogenously synthesized in all cells by a very complex pathway involving a group of nuclear genes that share high homology among
Juan Diego Hernández-Camacho   +4 more
doaj   +1 more source

Ubiquinone supplementation during lovastatin treatment: effect on LDL oxidation ex vivo1

open access: yesJournal of Lipid Research, 1998
A randomized, double-masked, placebo-controlled cross-over trial was carried out to evaluate whether ubiquinone supplementation (180 mg daily) corrects impaired defence against initiation of oxidation of low density lipoprotein (LDL) related to effective
Ari Palomäki   +3 more
doaj   +1 more source

Depletion and Supplementation of Coenzyme Q10 in Secondary Deficiency Disorders

open access: yesFrontiers in Bioscience-Landmark, 2022
Coenzyme Q10 (CoQ10) deficiency is broadly divided into two types, primary and secondary. Primary CoQ10 deficiencies are relatively rare disorders resulting from mutations in genes directly involved in the CoQ10 biosynthetic pathway, and are not a ...
David Mantle   +2 more
doaj   +1 more source

Effects of pravastatin and cholestyramine on products of the mevalonate pathway in familial hypercholesterolemia.

open access: yesJournal of Lipid Research, 1991
Patients with heterozygous familial hypercholesterolemia (n = 12) were treated either with pravastatin, a specific inhibitor of HMG-CoA reductase, or cholestyramine, followed by a period of combined treatment with both drugs.
PG Elmberger   +7 more
doaj   +1 more source

Predicting and Understanding the Pathology of Single Nucleotide Variants in Human COQ Genes

open access: yesAntioxidants, 2022
Coenzyme Q (CoQ) is a vital lipid that functions as an electron carrier in the mitochondrial electron transport chain and as a membrane-soluble antioxidant.
Sining Wang   +5 more
doaj   +1 more source

Ubiquinone in mitochondria of cytoplasmic mutants [PDF]

open access: yes, 1969
Ubiquinone in mitochondria of cytoplasmic ...
A. Kruszewska   +3 more
core   +1 more source

Ubiquinone Biosynthesis over the Entire O2 Range: Characterization of a Conserved O2-Independent Pathway

open access: yesmBio, 2019
Most bacteria can generate ATP by respiratory metabolism, in which electrons are shuttled from reduced substrates to terminal electron acceptors, via quinone molecules like ubiquinone.
Ludovic Pelosi   +16 more
doaj   +1 more source

The Modulation of Ubiquinone, a Lipid Antioxidant, on Neuronal Voltage-Gated Sodium Current

open access: yes, 2022
Ubiquinone, composed of a 1,4-benzoquinone and naturally produced in the body, actively participates in the mitochondrial redox reaction and functions as an endogenous lipid antioxidant, protecting against peroxidation in the pituitary-dependent hormonal
Sheng-Nan Wu   +5 more
core   +1 more source

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