Results 31 to 40 of about 114,066,372 (194)
A cross-metathesis approach to novel pantothenamide derivatives
Beilstein Journal of Organic Chemistry, 2016 Pantothenamides are known for their in vitro antimicrobial activity. Our group has previously reported a new stereoselective route to access derivatives modified at the geminal dimethyl moiety.
Jinming Guan +5 more
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Journal of Lipid Research, 2007 Lipid droplets (LDs) function as intracellular storage depots of neutral lipids. Recently, we identified long-chain acyl-coenzyme A synthetase 3 (ACSL3) as a major LD-associated protein in the human hepatocyte cell line HuH7.
Yasuyuki Fujimoto +10 more
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Journal of Biological Chemistry, 1967 Abstract An alkali-labile enzyme-coenzyme A intermediate has been isolated by molecular exclusion chromatography of succinyl-CoA-acetoacetate coenzyme A transferase after incubation with acetoacetyl-CoA or succinyl-CoA. Treatment of the intermediate with tritium-labeled sodium borohydride results in enzyme inactivation and incorporation of ...
L B, Hersh, W P, Jencks
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Biotransormations with plant coenzyme A-dependent acyltransferases [PDF]
, 2008 The acylation of plant natural products is widely observed in nature and this modification often confers novel bioactivities. In nature, each of these acylations is selectively catalysed by a coenzyme A-dependent acyltransferase and biotransformations ...
Cunningham, Oliver David
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Oleic acid is a potent inhibitor of fatty acid and cholesterol synthesis in C6 glioma cells
Journal of Lipid Research, 2007 Glial cells play a pivotal role in brain fatty acid metabolism and membrane biogenesis. However, the potential regulation of lipogenesis and cholesterologenesis by fatty acids in glial cells has been barely investigated.
Francesco Natali +3 more
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Coenzyme Q10 ameliorates BPA-induced apoptosis by regulating autophagy-related lysosomal pathways
Ecotoxicology and Environmental Safety, 2021 Bisphenol A (BPA) is a widely distributed environmental endocrine disruptor. The accumulation of BPA has been proved that produce various toxic effects both on human and animals. However, the strategies to reduce the damage of BPA on the body and related
Yuan Liu +7 more
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Coenzyme A corrects pathological defects in human neurons of PANK2‐associated neurodegeneration
EMBO Molecular Medicine, 2016 Pantothenate kinase‐associated neurodegeneration (PKAN) is an early onset and severely disabling neurodegenerative disease for which no therapy is available.
Daniel I Orellana +15 more
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Coenzyme A in Brain Biology and Neurodegeneration
BiomedicinesCoenzyme A (CoA) biology has been extensively studied in health and disease due to the central role of CoA in numerous metabolic and signalling processes.
Dejun Zhang +4 more
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Effect of Dietary Coenzyme Q10 on Cholesterol Metabolism in Growing Chickens
The Journal of Poultry Science, 2010 Coenzyme Q10 (CoQ10), a potent lipophilic antioxidant, is a naturally occurring compound with a ubiquitous distribution in nature and is used as a dietary supplement to combat aging.
Kazuhisa Honda +4 more
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Cleavage of Coenzyme B12 by Methylmalonyl Coenzyme A Mutase
Journal of Biological Chemistry, 1973 Abstract Methylmalonyl-CoA mutase-dependent cleavage of coenzyme B12 took place in the presence of succinyl-CoA, one of the substrates of the enzyme, and in the presence of malonyl-CoA, a competitive inhibitor (Ki 0.12 mm). Other competitive inhibitors of the reaction, including acetyl-CoA, propionyl-CoA, glutaryl-CoA, and CoA itself, did not replace ...
B M, Babior, A D, Woodams, J D, Brodie
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