Results 31 to 40 of about 148,184 (310)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Involvement of ACSL in local synthesis of neutral lipids in cytoplasmic lipid droplets in human hepatocyte HuH7

open access: yesJournal of Lipid Research, 2007
Lipid droplets (LDs) function as intracellular storage depots of neutral lipids. Recently, we identified long-chain acyl-coenzyme A synthetase 3 (ACSL3) as a major LD-associated protein in the human hepatocyte cell line HuH7.
Yasuyuki Fujimoto   +10 more
doaj   +1 more source

Isolation of an Enzyme-Coenzyme A Intermediate from Succinyl Coenzyme A-Acetoacetate Coenzyme A Transferase

open access: yesJournal of Biological Chemistry, 1967
Abstract An alkali-labile enzyme-coenzyme A intermediate has been isolated by molecular exclusion chromatography of succinyl-CoA-acetoacetate coenzyme A transferase after incubation with acetoacetyl-CoA or succinyl-CoA. Treatment of the intermediate with tritium-labeled sodium borohydride results in enzyme inactivation and incorporation of ...
L B, Hersh, W P, Jencks
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial [PDF]

open access: yes, 2009
OBJECTIVE: To evaluate the effectiveness of coenzyme Q(10) treatment in improving semen quality in men with idiopathic infertility. DESIGN: Placebo-controlled, double-blind randomized trial.
LENZI, Andrea   +9 more
core   +2 more sources

Oleic acid is a potent inhibitor of fatty acid and cholesterol synthesis in C6 glioma cells

open access: yesJournal of Lipid Research, 2007
Glial cells play a pivotal role in brain fatty acid metabolism and membrane biogenesis. However, the potential regulation of lipogenesis and cholesterologenesis by fatty acids in glial cells has been barely investigated.
Francesco Natali   +3 more
doaj   +1 more source

Analysis of the mechanosensor channel functionality of TACAN

open access: yeseLife, 2021
Mechanosensitive ion channels mediate transmembrane ion currents activated by mechanical forces. A mechanosensitive ion channel called TACAN was recently reported.
Yiming Niu   +6 more
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

The effect of the antioxidant, Coenzyme Q, on Coco-2 colon cells treated with iron to reduce lipid peroxidation [PDF]

open access: yes, 2002
Plan BThe objective of this study was to determine if Coenzyme Q10 (also known as ubiquinone) acting as an antioxidant, would protect against free radical damage to cell membranes that can cause cancer.
Johanknecht, Viva M.
core  

A Convenient Two-Step Synthesis of Coenzyme Q1

open access: yes, 2019
A convenient method for the preparation of Coenzyme Q1 from the cheap and readily available 3,4,5-Trimethoxytoluene was developed. CoQ1 was synthesized in moderate yield by a two-step procedure involving the key reaction of allyl bromide with CoQ0 ...
Wan-Yue, Luo   +4 more
core   +1 more source

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