Results 21 to 30 of about 114,066,372 (194)

The protective role of coenzyme Q10 and vitamin E on antioxidant defense system in the heart of cadmium treated rats

, 2002
Cadmium (Cd) is an important pollutant of environment which accwnulates in the liver and the kidneys, as well as in other tissues. Cd induces oxidative damage causing many metabolic, histological and pathological changes, such as nephrotoxicity ...
Maletić, Snežana, Žikić, Radoslav V., Štajn, Andraš Š., Ognjanović, Branka, Saičić, Zorica, Petrović, Vojislav M., Radojičić, Ratko, Pavlović, Slađan   +7 more
core   +5 more sources

The Role of Coenzyme Q10 against Cyclosporine-A Induced Cardiotoxicity in Adult Male Albino Rats (Histological and Toxicological Study) [PDF]

Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2013
Cyclosporine-A (CsA) has a potent immunosuppressive activity and is commonly used as anti-rejection drug after organ transplantation and for treatment of some autoimmune diseases. Several toxic effects on the cardiovascular system have been reported with
Ibrahim Awwad, Sahar Shaban, Siam M.G, Gehan Ahmed   +3 more
doaj   +1 more source

Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline [PDF]

, 2010
Previous studies of the effects of coenzyme Q10 and minocycline on mouse models of Huntington’s disease have produced conflicting results regarding their efficacy in behavioral tests.
Brunner Daniela, Menalled Liliana B., Brunner, D., Signer Ethan, Liliana B Menalled, Benjamin Zahasky, Ragland Natalie, Tobin Allan J., Allan J Tobin, Larry Park, Ragland, N., Minnich, J., Leeds, J., Daniela Brunner, Jennifer Goodman, Zahasky, B., Signer, E., Leeds Janet, Howland David, Zahasky Benjamin, Goodman, J., Tobin, A.J., Patry Monica, Minnich Jennie, Ethan Signer, Goodman Jennifer, Patry, M., Menalled, L.B., Lowden, Philip A.S., Jennie Minnich, Park Larry, Phillip A S Lowden, Howland, D., Park, L., Janet Leeds, Monica Patry, Lowden Phillip A. S., David Howland, Natalie Ragland   +38 more
core   +2 more sources

Oxalate-silica gel thin-layer system for free 2-hydroxy fatty acids and for fatty acyl coenzyme A

Journal of Lipid Research, 1972
The 2-hydroxy fatty acids tend to yield streaks in thin-layer chromatography on silica gel plates. If potassium oxalate is included with binder-free silica gel, good spots are obtained.
M. David Ullman, Norman S. Radin
doaj   +1 more source

The influence of coenzyme Q10 supplementation on antioxidant defense system in the liver of cadmium treated Rats

, 2000
Coenzyme Q10 in its reduced form (CoQ10Hz) is a powerful antioxidant. As an ant io x idant it is exploited either directly upon superoxide or indirectly on lipid radic als.
Štajn, Andraš Š., Žikić, Radoslav V., Ognjanović, Branka, Saičić, Zorica, Petrović, Vojislav M., Pavlović, Slađan   +5 more
core   +5 more sources

Characterization of Plasmodium falciparum Pantothenate Kinase and Identification of Its Inhibitors From Natural Products

Frontiers in Cellular and Infection Microbiology, 2021
Coenzyme A (CoA) is a well-known cofactor that plays an essential role in many metabolic reactions in all organisms. In Plasmodium falciparum, the most deadly among Plasmodium species that cause malaria, CoA and its biosynthetic pathway have been proven ...
Arif Nurkanto, Arif Nurkanto, Ghulam Jeelani, Herbert J. Santos, Yulia Rahmawati, Mihoko Mori, Mihoko Mori, Yumi Nakamura, Kana Goto, Yoko Saikawa, Takeshi Annoura, Yuzuru Tozawa, Takaya Sakura, Daniel Ken Inaoka, Kazuro Shiomi, Tomoyoshi Nozaki   +15 more
doaj   +1 more source

The Metabolism of Coenzyme A and Its Derivatives Plays a Crucial Role in Diseases

Frontiers in Bioscience-Landmark
Coenzyme A (CoA) functions as a crucial carrier of acyl groups within cells, playing a fundamental role in regulating acyl transfer reactions and participating in cellular metabolic processes.
Jumin Xie, Xingyuan Chen, Mei Zheng, Jingzhe Zhu, Hui Mao   +4 more
doaj   +1 more source

Isolating promoters from Corynebacterium ammoniagenes ATCC 6871 and application in CoA synthesis

BMC Biotechnology, 2019
Background Corynebacterium ammoniagenes is an important industrial organism that is widely used to produce nucleotides and the potential for industrial production of coenzyme A by C. ammoniagenes ATCC 6871 has been shown. However, the yield of coenzyme A
Yingshuo Hou, Siyu Chen, Jianjun Wang, Guizhen Liu, Sheng Wu, Yong Tao   +5 more
doaj   +1 more source

Analysis of the mechanosensor channel functionality of TACAN

eLife, 2021
Mechanosensitive ion channels mediate transmembrane ion currents activated by mechanical forces. A mechanosensitive ion channel called TACAN was recently reported.
Yiming Niu, Xiao Tao, George Vaisey, Paul Dominic B Olinares, Hanan Alwaseem, Brian T Chait, Roderick MacKinnon   +6 more
doaj   +1 more source

A Convenient Two-Step Synthesis of Coenzyme Q1 [PDF]

, 2019
A convenient method for the preparation of Coenzyme Q1 from the cheap and readily available 3,4,5-Trimethoxytoluene was developed. CoQ1 was synthesized in moderate yield by a two-step procedure involving the key reaction of allyl bromide with CoQ0 ...
Wan-Yue, Luo, Jin, Wang, Yi-Yu, Yan, Jian-Hua, Tian, Yan, Zhao   +4 more
core   +1 more source