Results 281 to 290 of about 559,012 (379)
Trapping interactions between catalytic domains and carrier proteins of modular biosynthetic enzymes with chemical probes. [PDF]
Gulick AM, Aldrich CC.
europepmc +1 more source
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
Characterization of native sterol carrier protein
Elizabeth Hansbury+3 more
openaire +3 more sources
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel+4 more
wiley +1 more source
Molecular characterization of an Escherichia coli mutant with a temperature‐sensitive malonyl coenzyme A‐acyl carrier protein transacylase [PDF]
Ira I. G. S. Verwoert+5 more
openalex +1 more source
The Effect of Divalent Cations on the Thermostability of Type II Polyketide Synthase Acyl Carrier Proteins. [PDF]
Rivas M+22 more
europepmc +1 more source
Establishment and biological characterization of radioresistant colorectal cancer cell lines
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu+10 more
wiley +1 more source