Dihydro-sphingosine 1-phosphate interacts with carrier proteins in a manner distinct from that of sphingosine 1-phosphate. [PDF]
Mishima Y+6 more
europepmc +1 more source
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren+8 more
wiley +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source
The Legionella pneumophila effector Lpg1137 is a homologue of mitochondrial SLC25 carrier proteins, not of known serine proteases. [PDF]
Gradowski M, Pawłowski K.
europepmc +1 more source
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui+5 more
wiley +1 more source
Effects of serum carrier proteins on the growth of pathogenic neisseriae with heme-bound iron.
David W. Dyer+2 more
openalex +2 more sources
Recognition of acyl carrier proteins by ketoreductases in assembly line polyketide synthases. [PDF]
Ostrowski MP, Cane DE, Khosla C.
europepmc +1 more source
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet+6 more
wiley +1 more source
Cyanobacterial Sfp-type phosphopantetheinyl transferases functionalize carrier proteins of diverse biosynthetic pathways. [PDF]
Yang G+6 more
europepmc +1 more source