Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The association between a carrier state of FMR1 premutation and numeric sex chromosome variations. [PDF]
J Assist Reprod Genet, 2023 Malcov M +7 more
europepmc +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gastroenterology Research and Practice, 2014 Aim. To investigate the relationship between hepatitis B e antigen seroconversion and the function of dendritic cells (DC) in patients with hepatitis B virus. Methods.
Chunjing Lin, Hai Zou, Shumin Wang
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Spontaneous curing of a minute virus of mice carrier state by selection of cells with an intracellular block of viral replication [PDF]
, 1986 Dina Ron, Jacob Tal
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Streptococcus equi subsp. zooepidemicus infection of pigs leads to shedding in faeces and a carrier state. [PDF]
Transbound Emerg Dis, 2022 Costa MO +3 more
europepmc +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Four-Wave Mixing Conversion in QD SOA: reservoir effects
مجلة علوم ذي قار, 2019 In this paper, it is present a model to simulate Four-wave mixing in quantum dot semiconductor optical amplifier, taking into account the influence of carrier heating at reservoir.
Ahmed H. Flayyih, Riyam H. Ali
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BACTERAL CARRIER STATE OR LATENT TUBERCULOSIS?
Acta Biomedica Scientifica, 2012 Lung resection specimens of 677 surgical patients were studied to determine the clinical meaning of the absence of Mycobacterium tuberculosis (MTB) in sputums of pulmonary tuberculosis patients, who show none of the clinical manifestations of ...
G. I. Alexeeva, A. F. Kravchenko
doaj