Results 141 to 150 of about 11,338,930 (230)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Carry-over effect of learned distractor suppression on visual working memory. [PDF]

Front Neurosci
George N, Patel PC.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Phenotypic plasticity shapes carry-over effects in sea rock-pool mosquitoes. [PDF]

Biol Open
Cordeschi G, Bisconti R, Mastrantonio V, Canestrelli D, Porretta D.   +4 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Cross‐contamination of non‐target feedingstuffs by salinomycin authorised for use as a feed additive ‐ Scientific Opinion of the Panel on Contaminants in the Food Chain

EFSA Journal, 2008
European Food Safety Authority (EFSA)
doaj   +1 more source

Carry-over effects between spring and autumn phenology differ among the world's biomes. [PDF]

Natl Sci Rev
Wu Z, Fu YH, Crowther TW, Renner SS, Vitasse Y, Mo L, Zou Y, Mirzagholi L, Li M, Rebindaine D, Gong Y, Guo Z, Wang N, Zohner CM.   +13 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Cross‐contamination of non‐target feedingstuffs by maduramicin authorised for use as a feed additive ‐ Scientific opinion of the Panel on Contaminants in the Food Chain

EFSA Journal, 2008
European Food Safety Authority (EFSA)
doaj   +1 more source

Clarifying Order and Carry-Over Considerations in Dual-Target MRgFUS for Parkinson's Disease. [PDF]

Eur J Neurol
Chen JC, Lu MK, Tsai CH.
europepmc   +1 more source