FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
, 1968 carry vWith a carry-over of fish in Newfoundland it was possible for the John and Jane to arrive at St. John's on May 22 with 300 hogsheads of salt from Lisbon, to leave on June 10 with 1,000 quintails of fish for Lisbon ....PRINTED ITEM W.
core
No "carry-over" effects of tracking devices on return rate and parameters determining reproductive success in once and repeatedly tagged common swifts (Apus apus), a long-distance migratory bird. [PDF]
Mov Ecol, 2022 Wellbrock AHJ, Witte K.
europepmc +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Clarifying Order and Carry-Over Effects in Sequential MRgFUS Thalamotomy and Pallidothalamic Tract Ablation. [PDF]
Eur J NeurolAubignat M.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Other title: Concealed Carry Licensing in Kansas
, 2015 Includes bibliographical references.A set of 5 documents provided by the Concealed Carry Licensing Unit, Office of the Attorney General, with resources and information on Concealed Carry Licensing in Kansas.Kansas Concealed Carry Licensing (September 10,
Kansas Office of the Attorney General. Concealed Carry Licensing Unit.
core
Randomised control trial on the sustained carry-over effects of pulsed electromagnetic field therapy for the treatment of Achilles tendinopathy. [PDF]
Sci RepKo VM, Fu SC, Yung PS, Ling SK.
europepmc +1 more source