Results 121 to 130 of about 19,362,621 (286)

The carry-over effect does not influence football results [PDF]

, 2010
In a round robin tournament, it is often believed that each team has an effect on its opponent which carries over to the next game of that opponent. Indeed, if team C plays against team A, and subsequently against team B, C's performance against B can be
Goossens, Dries, Spieksma, Frederik
core  

Carry-over effect of immunotherapy in patients with advanced hepatocellular carcinoma

Cancer Immunology, Immunotherapy
Abstract Background Combination immunotherapy is the current standard for treating advanced hepatocellular carcinoma (HCC). The response elicited by upfront immune checkpoint inhibitors (ICIs) might influence the efficacy of salvage therapy, a phenomenon known as the carry-over effect.
Chien-Huai Chuang, Ching-Tso Chen, Chih-Hung Hsu, Yu-Yun Shao   +3 more
openaire   +3 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Time-Varying Systematic Risk of Carry Trade Strategies [PDF]

This paper suggests a factor model for carry trade strategies where the regression coefficients are allowed to depend on market volatility and liquidity.
Paul Soderlind, Charlotte Christiansen, Angelo Ranaldo   +2 more
core  

Immediate and carry-over effects of perceived predation risk on communication behavior in wild birds

, 2015
Predation induces strong selection on phenotypic traits, affecting prey via consumptive and nonconsumptive effects. Communication is important for territorial behavior, but can increase susceptibility to predators.
Kaiser, Aurélien, Abbey-Lee, Robin, N., Dingemanse, Niels, J., Mouchet, Alexia   +3 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Heat wave impacts on crop‐pest dynamics are dependent upon insect ontogeny and plant resistance

Ecosphere
Heat waves, brief periods of unusually high temperatures, are damaging to agroecosystems and are increasing in frequency and intensity due to climate change. Despite growing appreciation for the threat that heat waves pose to agricultural sustainability,
Nalleli Carvajal Acosta, Luke N. Zehr, Joshua S. Snook, Zsofia Szendrei, Michael Kalwajtys, William C. Wetzel   +5 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source