Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Larval diet and temperature alter mosquito immunity and development: using body size and developmental traits to track carry-over effects on longevity. [PDF]
Mackay AJ +4 more
europepmc +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Time Constraints Modulate the Effects of Predator Cues and a Metal Across Life Stages in a Damselfly
Animals are increasingly exposed to multiple co‐occurring stressors. Environmental factors such as seasonal time constraints (TC), predation risk, and pollutants strongly influence fitness‐related traits in aquatic organisms. Yet, the interactive effects
Nermeen R. Amer +4 more
doaj +1 more source
The real-time and carry-over effects of injustice on performance and service quality in a ridesharing driver scenario. [PDF]
Lei X, Kaplan SA.
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Design and analysis of factorial sensory experiments with carry-over effects
International audienceA wine tasting study is used to illustrate how carry-over effects can occur in a sensory experiment with factorial treatments.
Monod, Herve, Durier, C., Bruetschy, A.
core
Comparison of Bayesian Networks, G-estimation and linear models to estimate causal treatment effects in aggregated N-of-1 trials with carry-over effects. [PDF]
Gärtner T +3 more
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Carry-Over Effects of Climate Variability at Breeding and Non-Breeding Grounds on Spring Migration in the European Wren Troglodytes troglodytes at the Baltic Coast. [PDF]
Gołębiewski I, Remisiewicz M.
europepmc +1 more source

