Results 91 to 100 of about 921,908 (302)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Worker's procedures whilst carrying out social inquiries

open access: yes, 2018
This Bachelor's thesis attends to the procedures of social workers from the Labour Office of the Czech Republic when carrying out social inquiries (investigations) of non-insurance social and welfare benefits.
MAŠÁT, David
core  

Limits for carrying out the specified control option at low, medium and high capacity levels.

open access: yes, 2018
Limits for carrying out the specified control option at low, medium and high capacity levels.
Marius Gilbert (118241)   +13 more
core   +1 more source

Factors Associated with the Chance of Carrying out a Primary Cesarean in a University Hospital. [PDF]

open access: yesRev Bras Ginecol Obstet, 2022
Wender MCO   +6 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Carrying out practice as form of professional preparation of music master

open access: yes, 1989
Посібник присвячений проблемі підвищення ефективності виконавської практики студентів – майбутніх вчителів музики. В роботі розкриваються роль та значення виконавської практики в системі професійно-педагогічної підготовки вчителя музики, розглядаються ...
Куришев, Євген Володимирович
core  

Probe into carrying out comfort nursing in patients undergoing operation

open access: yesHuli yanjiu, 2005
[目的]探讨将舒适护理运用于手术室整体护理中,观察和评价手术病人术中生理、心理舒适程度。[方法]选取5 12例择期胸外科、脑外科、妇产科及普通外科手术病人,随机分为观察组和对照组,观察组以萧丰富舒适护理模式为框架,制订一套舒适护理措施;对照组则按常规护理,采用自制的调查问卷进行病人自评和护士评价手术病人舒适度。[结果]经实施舒适护理措施后,观察组病人心理负担减轻,焦虑程度降低,能积极主动配合麻醉和手术,提高了对固定体位、疼痛的耐受性,舒适程度明显高于对照组(P
王玉   +4 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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