Results 51 to 60 of about 921,908 (302)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Men carrying out an inspection

open access: yes, 1916
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Armytage Family
core  

PROSECUTORAL SUPERVISION OVER THE EXECUTION OF LAWS BY THE BODIES CARRYING OUT OPERATIONAL-SEARCH ACTIVITIES [PDF]

open access: yes
One of the priority areas of activity of the prosecutor’s office is supervision over the implementation of laws by bodies carrying out operational investigative activities, during which problems arise related to its organization, implementation and ...
SHAPOVALOV YU.A., FEDORENKO YU.V.
core   +1 more source

Pre-stop MDA survey Phase 2—Carrying out an epidemiological survey.

open access: yes, 2023
Pre-stop MDA survey Phase 2—Carrying out an epidemiological survey.
Charles Mackenzie (569442)   +6 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Methodical instructions for carrying out control work on discipline «Аccounting»

open access: yes, 2023
Методичні вказівки до виконання контрольної роботи з дисципліни «Бухгалтерський облік» для здобувачів вищої освіти за освітнім ступенем «бакалавр» заочної форми навчання спеціальності 072 «Фінанси, банківська справа та страхування»/ Укл. О.П.
Зоря, Олександра Павлівна   +1 more
core  

Assessment form for carrying out the Comprehensive Assessment of Lowland Rivers (CALR).

open access: yes, 2023
Assessment form for carrying out the Comprehensive Assessment of Lowland Rivers (CALR).
Daniel Liberacki (14769057)   +3 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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