Results 91 to 100 of about 93,002 (309)
Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making
Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe +5 more
wiley +1 more source
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
Avaliou-se neste trabalho o crescimento de plantas de café cultivadas em um Latossolo Vermelho-Amarelo, com diferentes valores de pH e contaminado com resíduos de picloram.
L. D'Antonino +4 more
doaj +1 more source
Multi-Period Rent-Seeking Contests with Carryover: Theory and Experimental Evidence [PDF]
The majority of theoretical and experimental research stemming from Tullock’s (1980) model of rent-seeking considers static, single-period contests. This paper contributes to a growing body of research on multi-period rent-seeking contests by developing ...
John Cadigan +3 more
core
This review elucidates the formation pathways and detection technologies for ethyl carbamate, biogenic amines, and higher alcohols in Huangjiu. It concludes that integrated control frameworks are essential to decouple safety risks from the metabolic processes responsible for flavor development.
Lulu Liu +5 more
wiley +1 more source
Long‐term benefit from adjuvant tamoxifen therapy for ER+ HER2− breast cancer by PR positivity
What's New? Tamoxifen is a cornerstone of endocrine therapy for estrogen receptor (ER)‐positive/human epidermal growth factor receptor 2 (HER2)‐negative breast cancer. Its long‐term benefits, however, may vary by progesterone receptor (PR) status. Here, using data from the Stockholm tamoxifen trials, the authors evaluated whether PR expression predicts
Anna E. Nordenskjöld +8 more
wiley +1 more source
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon +5 more
wiley +1 more source
Endowment Effects and Contribution Strategies in Public Good Experiments
We investigate behavior in a laboratory public good experiment with unique endowment schemes that allow a wider range of contribution strategies than in standard voluntary contribution mechanism (VCM) experiments.
Cadigan, John J. +3 more
core
On MSE-optimal crossover designs [PDF]
In crossover designs, each subject receives a series of treatments one after the other. Most papers on optimal crossover designs consider an estimate which is corrected for carryover effects.
Kunert, Joachim, Neumann, Christoph
core
ABSTRACT Introduction In today's multiethnic schools, promoting youth connectedness and well‐being requires equipping students with the skills to navigate cultural diversity. Cultural intelligence (CQ), defined as the ability to interact effectively across diverse cultural contexts, is a key asset in this regard. This study explored whether the Italian
Xiwei Zhang +2 more
wiley +1 more source

