Carryover negligibility and relevance in bioequivalence studies [PDF]
The carryover effect is a recurring issue in the pharmaceutical field. It may strongly influence the final outcome of an average bioequivalence study. Testing a null hypothesis of zero carryover is useless: not rejecting it does not guarantee the non‐existence of carryover, and rejecting it is not informative of the true degree of carryover and its ...
Ocaña i Rebull, Jordi +2 more
openaire +3 more sources
Inclusive or Inauthentic? Consumer Scepticism Towards LGBTQ‐Themed Cause‐Related Marketing
ABSTRACT Cause‐related marketing (CRM) is widely used to signal corporate social responsibility and engage ethically motivated consumers, yet its effectiveness remains contested in identity‐sensitive domains such as LGBTQ inclusion. Drawing on Social Identity Theory and Attribution Theory, this research examines how LGBTQ cause identification ...
Wilson N. Ndasi
wiley +1 more source
Two experiments were conducted to verify whether the time of day at which a milk sample is collected and the possible carryover in the milking system may affect pregnancy-associated glycoproteins (PAG) levels and, consequently, the pregnancy test results
Helen K. da Silva +5 more
doaj +1 more source
Resíduos de aflatoxina B1 em fígado de codornas japonesas (Coturnix japonica) expostas a alimentos contaminados e à corticosterona exógena [PDF]
The combined effect of aflatoxin B1 (AFB1 ) exposition and stress induced by corticosterone (CORT) upon the residual aflatoxin levels in livers of Japanese quail was examined.
Chiacchiera, Stella Maris +4 more
core +1 more source
Optimal and efficient crossover designs for comparing test treatments with a control treatment
This paper deals exclusively with crossover designs for the purpose of comparing t test treatments with a control treatment when the number of periods is no larger than t+1. Among other results it specifies sufficient conditions for a crossover design to
Hedayat, A. S., Yang, Min
core +3 more sources
Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley +1 more source
Influence of pollen transport dynamics on sire profiles and multiple paternity in flowering plants. [PDF]
In many flowering plants individual fruits contain a mixture of half- and full- siblings, reflecting pollination by several fathers. To better understand the mechanisms generating multiple paternity within fruits we present a theoretical framework ...
Randall J Mitchell +3 more
doaj +1 more source
Beyond PBMCs: Polymer‐Based Cell Mimics for Robust TBNK Immunophenotyping Assay Validation
ABSTRACT Flow cytometry‐based TBNK immunophenotyping is widely used to assess immune status in research, clinical diagnostics, and cell therapy development. Biological control materials such as PBMCs often serve as physiologically relevant controls, but suffer from considerable variability due to donor differences, limited stability, and fluctuations ...
Swetha Pratyusha Gunturu +5 more
wiley +1 more source
Sensitivity of Leafy Vegetables to Simulated Mesotrione Residues in the Soil
Mesotrione is a triketone herbicide widely used for weed control in maize (Zea mays L.). In a bioassay conducted under controlled conditions, the simulated residual effects of mesotrione on leafy vegetables, including chard, lettuce, spinach, and endive ...
Milena Radivojević +2 more
doaj +1 more source
On Sloane's persistence problem [PDF]
We investigate the so-called persistence problem of Sloane, exploiting connections with the dynamics of circle maps and the ergodic theory of $\mathbb{Z}^d$ actions.
Charles Tresser, Edson De, Faria
core

