Results 81 to 90 of about 26,842 (252)

Counterbalancing for serial order carryover effects in experimental condition orders. [PDF]

Psychological Methods, 2012
Reactions of neural, psychological, and social systems are rarely, if ever, independent of previous inputs and states. The potential for serial order carryover effects from one condition to the next in a sequence of experimental trials makes counterbalancing of condition order an essential part of experimental design.
openaire   +2 more sources

Single‐subject designs in character education: Methods for rigorous, contextual, and practitioner‐led research

British Educational Research Journal, EarlyView.
Abstract Character education research is often constrained by blunt methodological tools. Surveys capture breadth without depth; case studies offer richness but lack replicability; and randomised controlled trials (RCTs), though indispensable at the policy level, are costly, disruptive and ill‐suited to everyday practice with individual pupils.
Shane McLoughlin
wiley   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

How Big Data Orientation and Affordances Drive Environmental Collaboration in Internationalizing SMEs

Business Strategy and the Environment, EarlyView.
ABSTRACT Building on the affordance and the resource‐based view (RBV) theories, we empirically test a conceptual model, which considers how big data orientation and affordances impact the development of environmental collaboration in internationalizing SMEs. The study considers the moderating effects of competitive intensity on the relationship between
Evangelia Katsikea, Marios Theodosiou, Oluyomi Alarape, Christophe Rethore, Eleanna Kafeza   +4 more
wiley   +1 more source

Generative Artificial Intelligence Performance on University‐Level Human Anatomy Examinations: A Structured Narrative Review and Proposed MATRIX‐Anatomy Framework

Clinical Anatomy, EarlyView.
ABSTRACT Generative artificial intelligence (GenAI) can perform strongly on written anatomy examinations, but whether such scores represent anatomical competence remains uncertain because results vary with the model, assessment, protocol, modality, scoring, and comparator.
Juan A. Sanchis‐Gimeno, Juan José Valenzuela‐Fuenzalida, Alejandro Bruna‐Mejías, Mathias Orellana‐Donoso, Glen J. Paton, Shahed Nalla   +5 more
wiley   +1 more source

Xylanase treatment of eucalypt kraft pulps: effect of carryover

Applied Microbiology and Biotechnology
Abstract The influence of pulp carryover on the efficiency of the xylanase (X) treatment of industrial unbleached and oxygen-delignified eucalypt kraft pulps (A1 and A2 pulps, with kappa number (KN) values of 16 and 10, respectively), collected at the same pulp mill, was studied regarding the consumption of bleaching chemicals ...
José M. S. Matos, Dmitry V. Evtuguin, António P. Mendes de Sousa, M. Graça V. S. Carvalho   +3 more
openaire   +2 more sources

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke, Diego M. Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane A. Sievi, Marco Di Donato, Anton Schmick, Jonas Herth, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +12 more
wiley   +1 more source

Marine heatwave conditions drive carryover effects in a temperate sponge microbiome and developmental performance. [PDF]

Proc Biol Sci, 2023
Strano F, Micaroni V, Thomas T, Woods L, Davy SK, Bell JJ.   +5 more
europepmc   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

Drug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza, Náthaly C. B. F. Santos, Rafael Lanaro, Sara E. Walton, Alex J. Krotulski, Barry K. Logan, Mauricio Yonamine, Jose Luiz Costa   +7 more
wiley   +1 more source